Results 91 to 100 of about 5,024,817 (231)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Long-term use of cover crops and no-till shift soil microbial community life strategies in agricultural soil

open access: yesPLoS ONE, 2018
Reducing tillage and growing cover crops, widely recommended practices for boosting soil health, have major impacts on soil communities. Surprisingly little is known about their impacts on soil microbial functional diversity, and especially so in ...
R. Schmidt   +4 more
semanticscholar   +1 more source

Rock debris on glaciers: a mechanism for reducing glacier sensitivity to climate change [PDF]

open access: yes, 2012
Rock debris covering a glacier surface affects the local melt rate by regulating the amount of solar energy available for melting. Supraglacial debris with a thickness of about 2 cm or more insulates the ice, thereby reducing the heat flux.
Herreid, Samuel
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A Head of State Leading by Example

open access: yesEmerging Infectious Diseases, 2022
Terence Chorba, José Esparza
doaj   +1 more source

Farmers' Willingness to Grow Cover Crops: Examining the Economic Factors of Adoption in Alabama [PDF]

open access: yes
The inclusion of cover crops in cropping systems brings both direct and indirect costs and benefits. The literature has shown that cover crops can improve soil conservation and productivity, potentially improving cash crop yields and decreasing cash crop
Bergtold, Jason S.   +2 more
core   +1 more source

Effect of White clover (Trifolium repens cv. Huia) cover crop on agronomic properties and soil biology in an organic peach orchard [PDF]

open access: yes, 2012
In orchards, cover crops are interesting alternative strategies to tillage or chemical herbicides for managing weeds in the tree row. However, little is known about the effect of cover crops on agronomic properties and soil biology in organic orchards ...
Bussi, Claude   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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