Results 1 to 10 of about 313,654 (268)

High Transmission Rates of Early Omicron Subvariant BA.2 in Bangkok, Thailand

Advances in Virology, 2023
The emergence of Omicron as the fifth variant of concern within the SARS-CoV-2 pandemic in late 2021, characterized by its rapid transmission and distinct spike gene mutations, underscored the pressing need for cost-effective and efficient methods to ...
Sininat Petcharat, Ananporn Supataragul, Piyapha Hirunpatrawong, Pattama Torvorapanit, Chonticha Klungthong, Piyawan Chinnawirotpisan, Sasiprapa Ninwattana, Nattakarn Thippamom, Leilani Paitoonpong, Gompol Suwanpimolkul, Watsamon Jantarabenjakul, Rome Buathong, Khajohn Joonlasak, Wudtichai Manasatienkij, Khwankamon Rattanatumhi, Napaporn Chantasrisawad, Nuntana Chumpa, Thomas S. Cotrone, Stefan Fernandez, Sira Sriswasdi, Supaporn Wacharapluesadee, Opass Putcharoen   +21 more
doaj   +1 more source

Monitoring the safety of COVID-19 vaccines in pregnancy in the US

Human Vaccines & Immunotherapeutics, 2021
Pregnant persons are at increased risk of severe illness from COVID-19. The first COVID-19 vaccines in the U.S. were authorized for emergency use in December 2020 and pregnant persons were eligible and could get vaccinated despite scarce safety data in ...
Pedro L. Moro, Lakshmi Panagiotakopoulos, Titilope Oduyebo, Christine K. Olson, Tanya Myers   +4 more
doaj   +1 more source

Ready-to-Eat Foods: A Potential Vehicle for the Spread of Coagulase-Positive Staphylococci and Antimicrobial-Resistant Staphylococcus aureus in Buea Municipality, South West Cameroon

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
The consumption of ready-to-eat (RTE) foods contaminated with coagulase-positive staphylococci (CoPS) and especially Staphylococcus aureus puts consumers at a potential risk of food-borne disease or colonization and subsequent infection.
Seraphine Nkie Esemu, Sally Tabe Njoh, Lucy Mande Ndip, Nene Kaah Keneh, Jerome Achah Kfusi, Achiangia Patrick Njukeng   +5 more
doaj   +1 more source

Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

npj Vaccines, 2022
Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA) vaccine, which encodes an alphavirus replicase that ...
Eugenia Z. Ong, Jia Xin Yee, Justin S. G. Ooi, Ayesa Syenina, Ruklanthi de Alwis, Shiwei Chen, Jean X. Y. Sim, Shirin Kalimuddin, Yan Shan Leong, Yvonne F. Z. Chan, Rose Sekulovich, Brian M. Sullivan, Kelly Lindert, Sean B. Sullivan, Pad Chivukula, Steven G. Hughes, Jenny G. Low, Eng Eong Ooi, Kuan Rong Chan   +18 more
doaj   +1 more source

Evolution and ecology of Jeilongvirus among wild rodents and shrews in Singapore

One Health Outlook, 2023
Background Jeilongvirus was proposed as a new genus within the Paramyxoviridae in 2018. The advancement in metagenomic approaches has encouraged multiple reports of Jeilongvirus detection following the initial species discovery, enriching species ...
Lena Ch’ng, Dolyce H.W. Low, Sophie A. Borthwick, Rong Zhang, Zoe A. Ong, Yvonne C.F. Su, Alan T. Hitch, Gavin J.D. Smith, Ian H. Mendenhall   +8 more
doaj   +1 more source

Climate Change and the Rise of Emerging and Re-Emerging Infectious Diseases in Africa: A Literature Review [PDF]

International Journal of Environmental Research and Public Health
Dennis Kithinji, Kizito Nsarhaza
exaly   +2 more sources

High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

Nature Communications, 2020
Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display
Seamus R. Morrone, Valerie S. Y. Chew, Xin-Ni Lim, Thiam-Seng Ng, Victor A. Kostyuchenko, Shuijun Zhang, Melissa Wirawan, Pau-Ling Chew, Jaime Lee, Joanne L. Tan, Jiaqi Wang, Ter Yong Tan, Jian Shi, Gavin Screaton, Marc C. Morais, Shee-Mei Lok   +15 more
doaj   +1 more source

Attenuated dengue viruses are genetically more diverse than their respective wild-type parents

npj Vaccines, 2021
Dengue poses a significant burden of individual health, health systems and the economy in dengue endemic regions. As such, dengue vaccine development has been an active area of research.
Amanda Makha Bifani, Milly M. Choy, Hwee Cheng Tan, Eng Eong Ooi   +3 more
doaj   +1 more source

Spike-Independent Infection of Human Coronavirus 229E in Bat Cells

Microbiology Spectrum, 2023
Bats are the reservoir for numerous human pathogens, including coronaviruses. Despite many coronaviruses having descended from bat ancestors, little is known about virus-host interactions and broader evolutionary history involving bats.
Marcus G. Mah, Martin Linster, Dolyce H. W. Low, Yan Zhuang, Jayanthi Jayakumar, Firdaus Samsudin, Foong Ying Wong, Peter J. Bond, Ian H. Mendenhall, Yvonne C. F. Su, Gavin J. D. Smith   +10 more
doaj   +1 more source

Dengue virus activates cGAS through the release of mitochondrial DNA

Scientific Reports, 2017
Cyclic GMP-AMP synthetase (cGAS) is a DNA-specific cytosolic sensor, which detects and initiates host defense responses against microbial DNA. It is thus curious that a recent study identified cGAS as playing important roles in inhibiting positive-sense ...
Bo Sun, Karin B. Sundström, Jun Jie Chew, Pradeep Bist, Esther S. Gan, Hwee Cheng Tan, Kenneth C. Goh, Tanu Chawla, Choon Kit Tang, Eng Eong Ooi   +9 more
doaj   +1 more source