Results 41 to 50 of about 1,171,014 (262)

SHERLOCK and DETECTR: CRISPR-Cas Systems as Potential Rapid Diagnostic Tools for Emerging Infectious Diseases

Journal of Clinical Microbiology, 2020
Infectious diseases are one of the most intimidating threats to human race, responsible for an immense burden of disabilities and deaths. Rapid diagnosis and treatment of infectious diseases offers a better understanding of their pathogenesis.
Mujahed I. Mustafa, Abdelrafie M Makhawi
semanticscholar   +1 more source

Reduced dengue virus pre-membrane protein-HMGB1 interaction activates host cell transcription to attenuate infection

npj Vaccines
To successfully complete an infection lifecycle, viruses have to avoid activating host antiviral and transcriptional responses to avoid disrupting cellular processes and cause premature host cell death.
Tanamas Siriphanitchakorn, Justin S. G. Ooi, Wy Ching Ng, Hwee Cheng Tan, Summer L. Zhang, Dorothy H. L. Ng, Xin Yap, Jia Xin Yee, Qiao Zheng, Yi Ting Tan, Eugenia Z. Ong, Kuan Rong Chan, Milly M. Choy, Eng Eong Ooi   +13 more
doaj   +1 more source

Forests and emerging infectious diseases: unleashing the beast within

Environmental Research Letters, 2020
Deforestation and associated changing landscapes are major components of environmental changes, with important implications for ecosystem functioning and biodiversity conservation. Tropical forests are hot spots of biodiversity and provide multiple goods
J. Guégan, A. Ayouba, J. Cappelle, B. de Thoisy   +3 more
semanticscholar   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Potential Role of ACE Polymorphisms in Severe Malaria: A Case Report

Case Reports in Infectious Diseases
This case aims to contribute to the debate about the role of ACE polymorphisms in malaria severity. Comprehensive studies are warranted to explore the genetic landscape in malaria-endemic regions and its implications for personalized treatment strategies.
Raffaella Pisapia, Andrea Pomicino, Giuseppina Minei, Isabella Iadevito, Alessandro Perrella   +4 more
doaj   +1 more source

Detection of a Reassortant H9N2 Avian Influenza Virus with Intercontinental Gene Segments in a Resident Australian Chestnut Teal

Viruses, 2020
The present study reports the genetic characterization of a low-pathogenicity H9N2 avian influenza virus, initially from a pool and subsequently from individual faecal samples collected from Chestnut teals (Anas castanea) in southeastern Australia ...
Tarka Raj Bhatta, Anthony Chamings, Jessy Vibin, Marcel Klaassen, Soren Alexandersen   +4 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Genetic diversity of the IC/3D7 allelic family of the merozoite surface protein 2 (MSP2) of Plasmodium falciparum and multiplicity of infection in four health facilities in the Mbouda Health District, Cameroon

Scientific Reports
The genetic variability of Plasmodium falciparum serves as an important marker of the parasite’s ability to adapt and develop resistance to antimalarial treatments. This study sought to evaluate the diversity of the P.
Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Toumko Towa Merveille, Tchuenkam Kom Pacome, Kenfack Tsague Mathieu, Gamago Nkadeu Guy-Armand, Djobo Abel, Guela Djoukou Mba Edna, Wansi Noumbissi Inès Sandra, Kana Tsague Yval, Haibo Hu   +10 more
doaj   +1 more source

Recent increase in the detection of human parainfluenza virus during the coronavirus disease-2019 pandemic in the Republic of Korea

Virology Journal, 2022
Background Since the onset of the coronavirus disease-2019 (COVID-19) pandemic, the prevalence of respiratory infectious diseases, particularly, the flu epidemic, has considerably decreased.
Heui Man Kim, Jee Eun Rhee, Nam-Joo Lee, Sang Hee Woo, Ae Kyung Park, Jaehee Lee, Cheon Kwon Yoo, Eun-Jin Kim   +7 more
doaj   +1 more source

Emerging infectious diseases and outbreaks: implications for women’s reproductive health and rights in resource-poor settings

Reproductive Health, 2020
This century is witnessing dramatic changes in the health needs of the world’s populations. The double burden of infectious and chronic diseases constitutes major causes of morbidity and mortality.
Vijay Kumar Chattu, S. Yaya
semanticscholar   +1 more source