Results 31 to 40 of about 1,171,014 (262)

SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

Nature Communications, 2020
During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected
Soren Alexandersen, Anthony Chamings, Tarka Raj Bhatta   +2 more
doaj   +1 more source

Understanding the failure of a behavior change intervention to reduce risk behaviors for avian influenza transmission among backyard poultry raisers in rural Bangladesh: a focused ethnography

BMC Public Health, 2016
Background The spread of the highly pathogenic avian influenza (HPAI) H5N1 virus among poultry and humans has raised global concerns and has motivated government and public health organizations to initiate interventions to prevent the transmission of ...
Nadia Ali Rimi, Rebeca Sultana, Kazi Ishtiak-Ahmed, Md Zahidur Rahman, Marufa Hasin, M. Saiful Islam, Eduardo Azziz-Baumgartner, Nazmun Nahar, Emily S. Gurley, Stephen P. Luby   +9 more
doaj   +1 more source

Serological differentiation between COVID-19 and SARS infections

Emerging Microbes and Infections, 2020
In response to the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, multiple diagnostic tests are required for acute disease diagnosis, contact tracing, monitoring asymptomatic infection rates and assessing herd immunity.
Wan Ni Chia, Chee Wah Tan, Randy Foo, Adrian Eng Zheng Kang, Yilong Peng, Velraj Sivalingam, Charles Tiu, Xin Mei Ong, Feng Zhu, Barnaby E. Young, Mark I.-C. Chen, Yee-Joo Tan, David C. Lye, Danielle E. Anderson, Lin-Fa Wang   +14 more
doaj   +1 more source

Attenuated dengue viruses are genetically more diverse than their respective wild-type parents

npj Vaccines, 2021
Dengue poses a significant burden of individual health, health systems and the economy in dengue endemic regions. As such, dengue vaccine development has been an active area of research.
Amanda Makha Bifani, Milly M. Choy, Hwee Cheng Tan, Eng Eong Ooi   +3 more
doaj   +1 more source

Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

mBio, 2020
To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. Here, we report a 382-nucleotide (nt) deletion in SARS-CoV-2 that truncates open reading frame 7b (ORF7b) and ORF8, removing ...
Yvonne C. F. Su, Danielle E. Anderson, Barnaby E. Young, Martin Linster, Feng Zhu, Jayanthi Jayakumar, Yan Zhuang, Shirin Kalimuddin, Jenny G. H. Low, Chee Wah Tan, Wan Ni Chia, Tze Minn Mak, Sophie Octavia, Jean-Marc Chavatte, Raphael T. C. Lee, Surinder Pada, Seow Yen Tan, Louisa Sun, Gabriel Z. Yan, Sebastian Maurer-Stroh, Ian H. Mendenhall, Yee-Sin Leo, David Chien Lye, Lin-Fa Wang, Gavin J. D. Smith   +24 more
doaj   +1 more source

Gene Updater: a web tool that autocorrects and updates for Excel misidentified gene names

Scientific Reports, 2022
Opening and processing gene expression data files in Excel runs into the inadvertent risk of converting gene names to dates. As pathway analysis tools rely on gene symbols to query against pathway databases, the genes that are converted to dates will not
Clara W. T. Koh, Justin S. G. Ooi, Gabrielle L. C. Joly, Kuan Rong Chan   +3 more
doaj   +1 more source

Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge

Emerging Microbes and Infections
Improved sanitation, increased access to health care, and advances in preventive and clinical medicine have reduced the mortality and morbidity rates of several infectious diseases. However, recent outbreaks of several emerging infectious diseases (EIDs)
H. Liao, Christopher J. Lyon, Bin-Wu Ying, Tony Y. Hu   +3 more
semanticscholar   +1 more source

BNT162b2 vaccine induced variant-specific immunity, safety and risk of Omicron breakthrough infection in children aged 5 to 11 years: a cohort study

Scientific Reports, 2023
There is little information on BNT162b2 vaccine-induced variant-specific immunogenicity, safety data and dynamics of breakthrough infections in pediatric populations. We addressed these questions using a prospective two dose BNT162b2 (10 mcg) vaccination
Chee Fu Yung, Nina Le Bert, Kai Qian Kam, Seyed Ehsan Saffari, Chee Wah Tan, Yun Yan Mah, Jinyan Zhang, Aileen Ying-Yan Yeoh, Feng Zhu, Smrithi Hariharaputran, Chia Yin Chong, Antonio Bertoletti, Linfa Wang   +12 more
doaj   +1 more source

The epidemiology of emerging infectious diseases and pandemics

Medicine, 2021
The spectrum of human pathogens and the infectious diseases they cause is continuously changing through evolution, selection and changes in the way human populations interact with their environment and each other.
H. V. van Doorn
semanticscholar   +1 more source

Dengue fever and chikungunya virus infections: identification in travelers in Uganda – 2017

Tropical Diseases, Travel Medicine and Vaccines, 2019
Arboviruses are (re-) emerging viruses that cause significant morbidity globally. Clinical manifestations usually consist of a non-specific febrile illness that may be accompanied by rash, arthralgia and arthritis and/or with neurological or hemorrhagic ...
John T. Kayiwa, Annet M. Nankya, Irene Ataliba, Charity A. Nassuna, Isaac E. Omara, Jeffrey W. Koehler, John M. Dye, Eric C. Mossel, Julius J. Lutwama   +8 more
doaj   +1 more source