Results 61 to 70 of about 5,024,817 (231)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Exploring character in As You Like It: exemplification level 6 (Active Shakespeare: Capturing evidence of learning) [PDF]
, 2010 "What is it about Providing active and engaging ways to integrate Shakespeare in the ongoing periodic assessment of pupils’ reading. What is it for?
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
, 2018 Interest in knowing more about the Earth’s land cover and how it has changed over time motivated the mission and sensor design of early terrestrial remote sensing systems. Rapid developments in computer hardware and software in the last four decades have
M. Wulder +4 more
semanticscholar +1 more source
The Arctic’s rapidly shrinking sea ice cover: a research synthesis
Climatic Change, 2012 The sequence of extreme September sea ice extent minima over the past decade suggests acceleration in the response of the Arctic sea ice cover to external forcing, hastening the ongoing transition towards a seasonally open Arctic Ocean.
J. Stroeve +5 more
semanticscholar +1 more source
The reversibility of sea ice loss in a state-of-the-art climate model [PDF]
, 2011 Rapid Arctic sea ice retreat has fueled speculation about the possibility of threshold (or ‘tipping point’) behavior and irreversible loss of the sea ice cover. We test sea ice reversibility within a state-of-the-art atmosphere–ocean global climate model
Armour, K. C. +4 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
[Review of the book \u3ci\u3eLabor Regulation in the Global Economy\u3c/i\u3e] [PDF]
, 2003 [Excerpt] This is a practical and useful volume on labor standards in today’s highly globalized world. An introduction is followed by ten chapters, some of them general, talking about the ILO or the WTO, and some more specific, focusing on the United ...
Fields, Gary S
core +1 more source