Results 51 to 60 of about 25,648 (218)
iMetaMed, EarlyView.This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu +7 more
wiley +1 more source
Cérebros, máquinas e psiquiatria [psiquiatria computacional]
Debates em Psiquiatria, 2012 A ideia de que os processos mentais são computacionais e, portanto, reprodutíveis artificialmente trouxe um grande impulso para a criação da Inteligência Artificial e se tornou um marco teórico que revitalizou a psicologia cognitiva, o conexionismo, a ...
Fernando Portela Camara
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal +5 more
wiley +1 more source
Journal of Periodontology, EarlyView.Abstract Background The clinical efficacy of growth factors in regenerative procedures may depend on both dosage and sustained delivery during critical phases of healing. This study aimed to evaluate in vitro release kinetics of platelet‐derived growth factor‐BB (PDGF‐BB) from various graft materials, including recombinant human PDGF‐BB (rhPDGF‐BB ...
Farahnaz Fahimipour +4 more
wiley +1 more source
Journal of Periodontology, EarlyView.Abstract Background This prospective study aimed to assess the clinical outcomes and patient‐related outcome measures (PROMs) of open flap debridement (OFD) alone versus open flap debridement with leukocyte–platelet‐rich fibrin (L‐PRF). Methods Twenty‐one patients were enrolled into a split‐mouth randomized clinical trial.
Jackson S. Sides +5 more
wiley +1 more source
Debates em PsiquiatriaO Departamento de Psicogeriatria, após análise crítica dos estudos pivotais e da literatura científica recente, emite as seguintes considerações sobre a aprovação e o uso clínico do donanemabe, anticorpo monoclonal direcionado à beta-amiloide, para ...
Tania Correa de Toledo Ferraz Alves +15 more
doaj +1 more source
Land Degradation &Development, EarlyView.ABSTRACT Land‐use changes related to cultivated land significantly affect the regional carbon budget in major grain‐producing regions, yet the ecological network characteristics of cultivated land carbon flows remain insufficiently understood. This study developed an integrated framework that combined ecological network analysis with spatial analysis ...
Xuehan Lin +4 more
wiley +1 more source
Huntingtin as an Actin Organizer: Structural and Functional Insights
Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To evaluate if the effect of low‐dose aspirin (LDA) commenced between 6 and 13 weeks of gestational age (GA) on preterm delivery (PTD) is modified by total exposure. Design Post hoc analysis of a randomized controlled trial. Setting Hospitals in low‐resource settings in Africa, Asia and Latin America.
Musaku Mwenechanya +89 more
wiley +1 more source
Parasites & Vectors, 2019 Background Bacillus thuringiensis israelensis (Bti) is a widely used mosquitocidal microbial pesticide due to its high toxicity. ATP-binding proteins (ABP) are prevalently detected in insects and are related to reaction against Bti toxins.
Guo-hui Zhao +14 more
doaj +1 more source