Results 101 to 110 of about 158,097 (358)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Ballast degradation : Effect of particle size and shape using Los Angeles Abrasion test and image analysis

, 2018
Ballast track is the most widely used track for the railway transport, and ballast bed plays a significant role to provide resistances during train operation. Generally, the ballast bed consists of crushed stones.
Yunlong Guo, V. Markine, Jianing Song, G. Jing   +3 more
semanticscholar   +1 more source

Abrasion-corrosion of downhole drill tool components

, 2008
The present work is a Schlumberger funded PhD project entitled ‘Abrasion-corrosion of downhole drill tool components’. The objective of this project was to replicate the wear-corrosion mechanisms of tungsten carbide (WC)-based hardmetals and coatings ...
Thakare, Mandar Rajiv
core  

Some views on the construction of bio-tribo-corrosion maps for Ti in Hanks solution : Particle concentration and applied loads effects

, 2011
Tribology of bio-implants is a major limiting issue in materials selection of the appropriate implant for the appropriate patient activity level [1].
Stack, Margaret, Huang, W., M.M. Stack, C. Hodge, Wang, G., W. Huang, G. Wang, Hodge, C.   +7 more
core   +1 more source

Effect of heat treatment and rotary swaging on microstructure and mechanical properties of 91W–Ni–Fe–Co alloy

Journal of Materials Research and Technology
In order to study the effects of deformation and heat treatment on the microstructure and properties of tungsten heavy alloys (WHAs), 91W-5.44Ni-0.99Fe-2.57Co alloy bars were prepared by powder metallurgy method combined with rotary swaging.
Shiru Liu, Zhou Li, Xuemeng Zhou, Lu Yang, Liujie Xu, Xiran Wang, Dabo Liu, Deze Yue, Shizhong Wei   +8 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Ação das soluções de bicarbonato de sódio e fluoretos frente a desafio erosivo e abrasivo, in vitro [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2015.Objetivo: O objetivo deste estudo in vitro foi avaliar os efeitos da solução de bicarbonato de ...
Noschang, Ricardo Augusto Tomaz
core  

Abrasion Pattern on Rubber

, 1953
It has been observed that an array of nearly parallel ridges is often produced by abrasion on rubber surfaces. This array is called the “abrasion pattern.” The ridges run at right angles to the direction of abrasion, and their profile is asymmetrical ...
A. Schallamach
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Abrasion in pyroclastic flows [PDF]

, 1992
The relative size of glass rims coating crystals in the matrix ash provides a semi-quantitative measure of abrasion of ash grains in pyroclastic flows.
Schmincke, Hans-Ulrich, Freundt, Armin
core   +1 more source