Results 41 to 50 of about 3,581,734 (300)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The influence of surface finishing of Paulownia Siebold et Zucc. on the mechanical properties of lacquered surface [PDF]

open access: yesGlasnik Šumarskog Fakulteta: Univerzitet u Beogradu, 2010
This paper presents the research of influence of sanding, staining and the use of polyurethane and acrylic coating on the adhesion, scratch resistance and abrasion resistance of the coating.
Jaić Milan, Dobić Jovan, Palija Tanja
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

THE METHOD OF MATHEMATICAL MODELING OF ICE ABRASIVE EFFECTS ON BERTHING FACILITIES

open access: yesInternational Journal of Advanced Studies, 2021
The ice cover has a significant abrasive effect on the surface of marine engineering structures. In areas with high dynamics of ice cover drift, one of the most important problems of providing load-bearing capacity of structural elements is to determine ...
Anton A. Zverev   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Abrasion resistance of camouflage coating systems

open access: yesTechnical Transactions
The aim of this article is to evaluate the abrasion resistance of camouflage coating systems according to the D4060-10 standard using the Taber Abraser.
Michalski Marek
doaj   +1 more source

Influences of test conditions of sandblasting on replicability of abrasion pattern of concrete subjected to hydrodynamic action

open access: yesCase Studies in Construction Materials, 2023
To determine the most suitable test conditions for sandblasting to evaluate the abrasion resistance against hydrodynamic action, a series of abrasion tests using hardened cement pastes with different water-cement ratios were performed under multiple ...
K. Ueno   +6 more
doaj   +1 more source

Abrasive Elements and Abrasion Resistance Tests for Car Seat Upholstery [PDF]

open access: yesJournal of Engineered Fibers and Fabrics, 2013
The weight of textile components in automobiles is expected to rise to 35 kg by 2020, and the average lifetime of a vehicle is about 12 years. Car seats are the most important part of the interior decoration, and polyester is the most widely used material in car seat covering.
Jerkovic, Ivona   +3 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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