Results 21 to 30 of about 22,673 (260)
BioResources, 2015 The effects of pressure, feed rate, and abrasive mass flow rate on surface roughness were investigated during abrasive water cutting of recombinant bamboo. Two different thicknesses (10 mm and 15 mm) of recombinant bamboo were cut in the longitudinal and
Rongrong Li +6 more
doaj +1 more source
Crystals, 2023 The titanium alloy artificial knee joint is used extensively in the current medical industry due to its distinct characteristics and properties that are like the real human knee joint, but it does need to be polished to improve its performance and ...
Renquan Ji +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Jin'gangshi yu moliao moju gongcheng, 2020 Abrasive grains, with different sizes and shapes, were used to cut titanium alloy on a cutting platform to study the effect of impingement jet on the micro-morphologies of alloy surface.
CHEN Xianjun, ZHOU Wen, XU Maoqin
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Effect of abrasive size and matrix hardness on fixed abrasive polishing of YAG crystal
Jin'gangshi yu moliao moju gongcheng, 2020 Yttrium aluminum garnet (YAG) is a kind of hard-brittle and difficult-to-machine material with wide application. Its polishing process is complicated and inefficient.
MING Shun +5 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
XV. Experiments on the friction and abrasion of the surfaces of solids [PDF]
Philosophical Transactions of the Royal Society of LondonAbstract The paper now offered to the consideration of the Royal Society, comprises the results of part of a series of experiments undertaken in the year 1825, with a view to determine the measure of the retardations of bodies in motion, when affected by the attrition of their surfaces, and by mediums of different densities.
openaire +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source