Results 21 to 30 of about 21,724 (259)
The effects of pressure, feed rate, and abrasive mass flow rate on surface roughness were investigated during abrasive water cutting of recombinant bamboo. Two different thicknesses (10 mm and 15 mm) of recombinant bamboo were cut in the longitudinal and
Rongrong Li +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The titanium alloy artificial knee joint is used extensively in the current medical industry due to its distinct characteristics and properties that are like the real human knee joint, but it does need to be polished to improve its performance and ...
Renquan Ji +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Abrasive grains, with different sizes and shapes, were used to cut titanium alloy on a cutting platform to study the effect of impingement jet on the micro-morphologies of alloy surface.
CHEN Xianjun, ZHOU Wen, XU Maoqin
doaj
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
XV. Experiments on the friction and abrasion of the surfaces of solids [PDF]
Abstract The paper now offered to the consideration of the Royal Society, comprises the results of part of a series of experiments undertaken in the year 1825, with a view to determine the measure of the retardations of bodies in motion, when affected by the attrition of their surfaces, and by mediums of different densities.
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
CHANGING BARREL SURFACE MACROGEOMETRY THROUGH VIBROFINISHING TREATMENT ON FLAT OSCILLATING SURFACE
The experimental results of barrel vibrofinishing (grinding-in) through rolling on the flat oscillating surface are presented. The given method is nonconventional, and it includes both finishing methods and vibrotransportation.
Nikolay V. Mategorin +1 more
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