Results 291 to 300 of about 2,080,423 (380)
Distortion in the Communication of Nonsignificant Primary Outcomes: The Spin Strategy in Multiple Sclerosis Trials
Annals of Neurology, EarlyView.Objective
Spin refers to reporting strategies that highlight the benefits of an experimental treatment or divert attention from nonsignificant primary outcomes. To assess spin in randomized clinic trials (RCTs) on pharmaceutical efficacy in multiple sclerosis (MS) and explore associated factors.Marta Mascareñas‐García, Alejandro Rivero‐de‐Aguilar, Cristina Candal‐Pedreira, Guadalupe García, Carla Guerra‐Tort, Lucía Martín‐Gisbert, Julia Rey‐Brandariz, Mónica Pérez‐Ríos Ríos, Beatriz Casal‐Acción, María Isolina Santiago‐Pérez, Leonor Varela‐Lema +10 morewiley +1 more sourcePretreatment behavior and subsequent medication effects in childhood absence epilepsy
, 2017 Ruth C. Shinnar, Shlomo Shinnar, Avital Cnaan, Peggy O. Clark, Dennis Dlugos, Deborah G. Hirtz, Fengming Hu, Chunyan Liu, David Masur, Erica Weiss, Tracy A. Glauser, Harry S. Abram, Ellen Albers, Samar J. Bahna, Karen Ballaban‐Gil, José E. Barrera, Tekolla Belaineh, Mary Bertrand, Hal Blumenfeld, Sarah Borror, Charlie Borzy, Susan Brantz, Candace Cardoza, Kevin Chapman, Harry T. Chugani, Robert R. Clancy, Peggy O. Clark, Yong Collins, Terrie Conklin, Joan A. Conry, Patricia K. Crumrine, Jason Czachor, Maryland Dean, Sandra Dewar, Michael Duchowny, Deborah Dye, Tammy L. Eaton, Mary Jo Elgie, Michelle Ellis, Roy D. Elterman, Daniella Escobedo, Andrew Francis, L. Matthew Frank, Tracy A. Glauser, Hilary Gray, La June Grayson, May L. Griebel, Laurie Guidry, Samantha Hagopian, Jennifer Haky, Amelia Halac, Angel Hernandez, Howard Lee, Krisa Hoyle Elgin, Pong Kankirawatana, Kent R. Kelley, Juli Kidd, Divya S. Khurana, Paul M. Levisohn, Donna Lowery, Ricardo Luzondo, Mary Lou Maher, Ángela Martínez, Karen McEwen, Sarah J. McVey, Mary Miceli, Daniel K. Miles, Jennifer L. Monahan, Elena Martín Morales, Dianne Morus, C de B Mott, JoAnn Narus, Mark Nespeca, Edward J. Novotny, Suzanne Oken, Juliann Paolicchi, Bryan Philbrook, Tami Quintero, Amber Reese-Porter, Jong M. Rho, Tracee Ridley-Pryor, Angela Riggs, Colin Roberts, Kathy Romine, Véronique Ruppe, Russell P. Saneto, Raman Sankar, Mark S. Scher, Rebecca Schultz, Michael Schwabe, Dina Schwam, Sagar Shah, Gregory B. Sharp, Rolla Shbarou, Ruth C. Shinnar, Shlomo Shinnar, Márcio Sotero de Menezes, Donovan Stock, Christina Lopez Talley, Susanna Taylor +99 moreopenalex +2 more sourcesIntranasal Seletracetam in a Patient with Reading Epilepsy: First‐in‐Human Use to Prevent Reflex Seizures
Annals of Neurology, EarlyView.We report the first human use of intranasal seletracetam (SEL) to prevent reflex seizures. A patient with epilepsy with reading‐induced seizures on levetiracetam (3,000 mg/day) continued to experience reading‐induced focal seizures with preserved consciousness.Matthias J. Koepp, Kai‐Nicolas Poppert, Thomas Felder, Aljoscha Thomschewski, Sandra Lafenthaler, Pavel Klein, Alexander Rotenberg, Wolfgang Löscher, Chris Rundfeldt, Eugen Trinka +9 morewiley +1 more sourceHuman Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice
Annals of Neurology, EarlyView.Objective
Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier +19 morewiley +1 more sourceAltered directed functional connectivity in temporal lobe epilepsy in the absence of interictal spikes: A high density EEG study
Epilepsia, 2016 A. Coito, M. Genetti, F. Pittau, G. Iannotti, Aljoscha Thomschewski, Y. Höller, E. Trinka, R. Wiest, M. Seeck, C. Michel, Gijs Plomp, S. Vulliémoz +11 moresemanticscholar +1 more source
