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Therapeutic Options for Childhood Absence Epilepsy [PDF]

open access: yesPediatric Reports, 2021
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years.
Victoria Elisa Rinaldi   +3 more
doaj   +3 more sources

Effects of the T-type calcium channel CaV3.2 R1584P mutation on absence seizure susceptibility in GAERS and NEC congenic rats models

open access: yesNeurobiology of Disease, 2023
Rationale: Low-voltage-activated or T-type Ca2+ channels play a key role in the generation of seizures in absence epilepsy. We have described a homozygous, gain of function substitution mutation (R1584P) in the CaV3.2 T-type Ca2+ channel gene (Cacna1h ...
Pablo M. Casillas-Espinosa   +8 more
doaj   +1 more source

EEG phase synchronization during absence seizures

open access: yesFrontiers in Neuroinformatics, 2023
Absence seizures—generalized rhythmic spike-and-wave discharges (SWDs) are the defining property of childhood (CAE) and juvenile (JAE) absence epilepsies. Such seizures are the most compelling examples of pathological neuronal hypersynchrony.
Pawel Glaba   +9 more
doaj   +1 more source

Prognostic Factors for Absence Epilepsy in Childhood [PDF]

open access: yesAnnals of Child Neurology, 2019
Purpose Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary.
So Young Kang   +5 more
doaj   +1 more source

Syndromic classification of patients with typical absence seizures [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2003
The aim of this study is to compare ILAE classification (1989) and Panayiotopoulos' criteria (1997) for absence epilepsies. We studied 455 typical absences (ILAE, 1981) by video-EEG in 43 patients with normal neurological and neuroradiological ...
Laura M.F.F. Guilhoto   +2 more
doaj   +1 more source

Ethosuximide vs Valproate Long-term Remission of Absence Epilepsy

open access: yesPediatric Neurology Briefs, 2014
Investigators from the Epilepsy Center, Lurie Children's Hospital of Chicago, and Yale School of Medicine, New Haven, CT, examined the possible association between long-term seizure outcome of childhood absence epilepsy (CAE) and the initial treatment ...
J Gordon Millichap, John J Millichap
doaj   +1 more source

Frontal-Temporal Brain Volumes in Absence Epilepsy

open access: yesPediatric Neurology Briefs, 2009
Fronto-temporal brain volumes and their association with clinical and psychological variables in children, aged 7.5-11.8 years, with childhood absence epilepsy (CAE) were compared to age and gender-matched children without epilepsy.
J Gordon Millichap
doaj   +1 more source

Prognosis of Early Onset Absence Epilepsy

open access: yesPediatric Neurology Briefs, 2013
Investigators from University of Chieti and several other centers in Italy conducted a multicenter retrospective 36-month follow-up study of the electroclinical course of epilepsy in all children with typical absence seizures (TAS) starting in the first ...
J Gordon Millichap
doaj   +1 more source

Concomitant Absence and Rolandic Epilepsy

open access: yesPediatric Neurology Briefs, 1998
Of 80 children with absence epilepsy (CAE) and 42 with Rolandic epilepsy (BECCT), five (3 girls and 2 boys) had both syndromes, in a study at the University of Berne, Switzerland.
J Gordon Millichap
doaj   +1 more source

Treatment priorities for idiopathic generalized epilepsy

open access: yesЭпилепсия и пароксизмальные состояния, 2021
The report presents the current principles of treatment of various types of epileptic seizures and forms of epilepsy. High efficacy and good tolerability in mono- and combination therapy with lamotrigine are shown, including its beneficial effects on ...
K. Yu. Mukhin
doaj   +1 more source

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