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Therapeutic Options for Childhood Absence Epilepsy [PDF]
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years.
Victoria Elisa Rinaldi +3 more
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Rationale: Low-voltage-activated or T-type Ca2+ channels play a key role in the generation of seizures in absence epilepsy. We have described a homozygous, gain of function substitution mutation (R1584P) in the CaV3.2 T-type Ca2+ channel gene (Cacna1h ...
Pablo M. Casillas-Espinosa +8 more
doaj +1 more source
EEG phase synchronization during absence seizures
Absence seizures—generalized rhythmic spike-and-wave discharges (SWDs) are the defining property of childhood (CAE) and juvenile (JAE) absence epilepsies. Such seizures are the most compelling examples of pathological neuronal hypersynchrony.
Pawel Glaba +9 more
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Prognostic Factors for Absence Epilepsy in Childhood [PDF]
Purpose Childhood absence epilepsy (CAE) is a common form of idiopathic generalized epilepsy with onset middle childhood and has typically a good prognosis, but remission rates vary.
So Young Kang +5 more
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Syndromic classification of patients with typical absence seizures [PDF]
The aim of this study is to compare ILAE classification (1989) and Panayiotopoulos' criteria (1997) for absence epilepsies. We studied 455 typical absences (ILAE, 1981) by video-EEG in 43 patients with normal neurological and neuroradiological ...
Laura M.F.F. Guilhoto +2 more
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Ethosuximide vs Valproate Long-term Remission of Absence Epilepsy
Investigators from the Epilepsy Center, Lurie Children's Hospital of Chicago, and Yale School of Medicine, New Haven, CT, examined the possible association between long-term seizure outcome of childhood absence epilepsy (CAE) and the initial treatment ...
J Gordon Millichap, John J Millichap
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Frontal-Temporal Brain Volumes in Absence Epilepsy
Fronto-temporal brain volumes and their association with clinical and psychological variables in children, aged 7.5-11.8 years, with childhood absence epilepsy (CAE) were compared to age and gender-matched children without epilepsy.
J Gordon Millichap
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Prognosis of Early Onset Absence Epilepsy
Investigators from University of Chieti and several other centers in Italy conducted a multicenter retrospective 36-month follow-up study of the electroclinical course of epilepsy in all children with typical absence seizures (TAS) starting in the first ...
J Gordon Millichap
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Concomitant Absence and Rolandic Epilepsy
Of 80 children with absence epilepsy (CAE) and 42 with Rolandic epilepsy (BECCT), five (3 girls and 2 boys) had both syndromes, in a study at the University of Berne, Switzerland.
J Gordon Millichap
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Treatment priorities for idiopathic generalized epilepsy
The report presents the current principles of treatment of various types of epileptic seizures and forms of epilepsy. High efficacy and good tolerability in mono- and combination therapy with lamotrigine are shown, including its beneficial effects on ...
K. Yu. Mukhin
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