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Duration matters: anticonvulsant therapy linked to bone loss in interim cross-sectional study [PDF]
Consortium PsychiatricumBACKGROUND: Anticonvulsants are widely used in treating patients with mental and neurological disorders. Their long-term use increases the risk of a decrease in bone mineral density (BMD) and low-energy fractures. Despite the growing number of studies of
Natalia A. Sivakova +8 more
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Five years of a single burn center experience with toxic epidermal necrolysis: retrospective study of causative drugs and the clinical outcome [PDF]
Reviews in Clinical Medicine, 2022 Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, but potentially life-threatening reactions to medications. Both conditions have significant morbidity and mortality.
Alireza Sedaghat +5 more
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Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
Frontiers in Pharmacology, 2021 AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi +4 more
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Refractory and super-refractory status epilepticus and evidence for the use of ketamine: a scope review [PDF]
Journal of Neurocritical Care, 2023 Status epilepticus (SE) is a neurological emergency with serious consequences for neuronal tissues, therefore, it is considered the most serious manifestation of epilepsy.
Luis Espinosa +3 more
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Role of Anticonvulsants in the Management of AIDS related Seizures
Frontiers in Neurology, 2014 Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI +1 more
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The Challenges of Children with Bipolar Disorder
Medicina, 2021 Childhood onset bipolar disorder (CO-BD) presents a panoply of difficulties associated with early recognition and treatment. CO-BD is associated with a variety of precursors and comorbidities that have been inadequately studied, so treatment remains ...
Robert M. Post, Heinz Grunze
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Anticonvulsants Following Craniotomy
Pediatric Neurology Briefs, 1992 A randomized prospective clinical trial of carbamazepine or phenytoin for 6 or 24 months including a control no-treatment group is reported in 276 post-craniotomy patients at the Walton Hospital, Liverpool, England.
J Gordon Millichap
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Anticonvulsants and Serum Cholesterol
Pediatric Neurology Briefs, 1992 The effect of antiepileptic drugs (AED) on total cholesterol, high density lipoprotein (HDL) cholesterol and triglycerides was studied in 208 epileptic children compared with 175 normal children at the University of Bologna, Italy.
J Gordon Millichap
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Neuropsychological Effects of Anticonvulsants
Pediatric Neurology Briefs, 2015 Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnosed focal ...
Lindsey Morgan, Alexandra Shaw
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Psychiatry and Clinical Psychopharmacology, 2021 Many anticonvulsant agents have been found to be effective in the treatment of psychiatric disorders; especially the affective disorders. Among these agents, carbamazepine, valporic acid and clonazepam were discussed for their effects in psychiatric ...
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