Results 1 to 10 of about 47,981 (309)
Recent developments on triazole nucleus in anticonvulsant compounds: a review
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Epilepsy is one of the common diseases seriously threatening life and health of human. More than 50 million people are suffering from this condition and anticonvulsant agents are the main treatment.
Ming-Xia Song, Xian-Qing Deng
exaly +2 more sources
Anticonvulsants in pregnancy [PDF]
Medical Journal of Australia, 1991 To review the potential problems and their management associated with the use of anticonvulsant drugs during pregnancy.Studies published between 1968 and 1990 assessing the effect of pregnancy on the pharmacokinetics of anticonvulsant drugs, the teratogenicity of anticonvulsants, breast feeding and anticonvulsants and use of the oral contraceptive pill
C J, Kilpatrick, R F, Moulds
openaire +4 more sources
Acetone as an Anticonvulsant [PDF]
Epilepsia, 2008 SummaryRecent interest in the anticonvulsant effects of acetone has stemmed from studies related to the ketogenic diet (KD). The KD, a high‐fat diet used to treat drug‐resistant seizures, raises blood and brain levels of three ketones: beta‐hydroxybutyrate, acetoacetate, and acetone.
Sergei, Likhodii +2 more
openaire +2 more sources
EXCLI Journal : Experimental and Clinical Sciences, 2023 Agonists of Benzodiazepine (BZD) receptor are exhaustively used in the control of muscle spasms, seizure, anxiety, and insomnia. BZDs have some unwanted effects; therefore, the development of new BZD receptor agonists with better efficacy and fewer ...
Elham Rezaee +7 more
doaj +1 more source
Anticonvulsants for fibromyalgia [PDF]
Cochrane Database of Systematic Reviews, 2013 Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. People often report high disability levels and poor health-related quality of life (HRQoL). Drug therapy focuses on reducing key symptoms and disability, and improving HRQoL.
Nurcan, Üçeyler +3 more
openaire +2 more sources
Salvinorin A Does Not Affect Seizure Threshold in Mice
Molecules, 2020 The κ-opioid receptor has recently gained attention as a new molecular target in the treatment of many psychiatric and neurological disorders including epilepsy.
Katarzyna Socała +2 more
doaj +1 more source
Inhibitory Effect of Eslicarbazepine Acetate and S-Licarbazepine on Nav1.5 Channels
Frontiers in Pharmacology, 2020 Eslicarbazepine acetate (ESL) is a dibenzazepine anticonvulsant approved as adjunctive treatment for partial-onset epileptic seizures. Following first pass hydrolysis of ESL, S-licarbazepine (S-Lic) represents around 95% of circulating active metabolites.
Theresa K. Leslie +5 more
doaj +1 more source
Sodium Valproate Induced Alopecia: A Case Series [PDF]
Journal of Clinical and Diagnostic Research, 2017 Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect.
Sereen Rose Thomson +2 more
doaj +1 more source
Extract of Euterpe oleracea Martius Stone Presents Anticonvulsive Activity via the GABAA Receptor
Frontiers in Cellular Neuroscience, 2022 Epilepsy is one of the most common neurological diseases globally, resulting from a disorder in brain activity. This condition can be triggered by birth trauma, traumatic brain injury (TBI), infections of the brain and stroke. More than 70 million people
Nilton Akio Muto +6 more
doaj +1 more source
Neurobiology of Disease, 2014 Viral infection of the CNS can result in encephalitis and acute seizures, increasing the risk for later-life epilepsy. We have previously characterized a novel animal model of temporal lobe epilepsy that recapitulates key sequela in the development of ...
Anthony D. Umpierre +8 more
doaj +1 more source