Results 1 to 10 of about 84,044 (310)
Recent developments on triazole nucleus in anticonvulsant compounds: a review
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Epilepsy is one of the common diseases seriously threatening life and health of human. More than 50 million people are suffering from this condition and anticonvulsant agents are the main treatment.
Xianqing Deng, Ming-Xia Song
exaly +3 more sources
Anticonvulsants in pregnancy [PDF]
Medical Journal of Australia, 1991 To review the potential problems and their management associated with the use of anticonvulsant drugs during pregnancy.Studies published between 1968 and 1990 assessing the effect of pregnancy on the pharmacokinetics of anticonvulsant drugs, the teratogenicity of anticonvulsants, breast feeding and anticonvulsants and use of the oral contraceptive pill
C J, Kilpatrick, R F, Moulds
openaire +4 more sources
Molecules, 2021 Rosa webbiana L. (Rosaceae) is one of the least reported and most understudied members of this family. It is native to the Himalayan regions of Pakistan and Nepal.
Anum Firdous +10 more
doaj +1 more source
Treating Epilepsy with Natural Products: Nonsense or Possibility?
Pharmaceuticals, 2023 Epilepsy is a neurological disease characterized by recurrent seizures that can lead to uncontrollable muscle twitching, changes in sensitivity to sensory perceptions, and disorders of consciousness.
Milan Malaník +5 more
doaj +1 more source
Thiazole Ring—A Biologically Active Scaffold
Molecules, 2021 Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical applications. Its derivatives have a wide range of biological activities such as antioxidant, analgesic, and antimicrobial including antibacterial, antifungal ...
Anthi Petrou +2 more
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Acetone as an Anticonvulsant [PDF]
Epilepsia, 2008 SummaryRecent interest in the anticonvulsant effects of acetone has stemmed from studies related to the ketogenic diet (KD). The KD, a high‐fat diet used to treat drug‐resistant seizures, raises blood and brain levels of three ketones: beta‐hydroxybutyrate, acetoacetate, and acetone.
Sergei, Likhodii +2 more
openaire +2 more sources
Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
Frontiers in Pharmacology, 2021 AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi +4 more
doaj +1 more source
Developmental Toxicity Study of DL-4-Hydroxy-4-Phenylhexanamide (DL-HEPB) in Rats
Life, 2023 Antiepileptic drugs affect embryonic development when administered during pregnancy, generating severe alterations, such as as cleft lip, spina bifida, heart abnormalities, or neuronal alterations.
José Melesio Cristóbal-Luna +5 more
doaj +1 more source
Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an antispasmodic, mild analgesic, to cure intercostal neuralgia, headaches, migraine,
Mahboobeh Ghasemzadeh Rahbardar +1 more
doaj +1 more source
Anticonvulsants for fibromyalgia [PDF]
Cochrane Database of Systematic Reviews, 2013 Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. People often report high disability levels and poor health-related quality of life (HRQoL). Drug therapy focuses on reducing key symptoms and disability, and improving HRQoL.
Nurcan, Üçeyler +3 more
openaire +2 more sources