Results 21 to 30 of about 47,981 (309)
Scientia Pharmaceutica, 2023 Mental and neurological disorders are conditions that affect thoughts, emotions, behavior, and relationships. Malpighia mexicana A. Juss. is a plant used in Mexican traditional medicine for the treatment of such disorders.
Dante Avilés-Montes +11 more
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Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]
, 2014 Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
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The Effects of Valproic Acid on Appetitive and Aversive Instrumental Learning in Adult Rats
Frontiers in Behavioral Neuroscience, 2014 Antiepileptic medications are the frontline treatment for seizure conditions. However, these medications are not without cognitive side effects. Previously, our laboratory reported learning deficits in phenytoin and carbamazepine-treated rats.
John Joseph Orczyk +4 more
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The teratogenicity of anticonvulsant drugs [PDF]
, 2001 Background: The frequency of major malformations, growth retardation, and hypoplasia of the mid-face and fingers, known as anticonvulsant embryopathy, is increased in infants exposed to anticonvulsant drugs in utero.
Ryan, LM +6 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Histamine H3 receptors (H3R) antagonists/inverse agonists are becoming a promising therapeutic approach for epilepsy. In this article, novel nonimidazole H3R antagonists/inverse agonists have been designed and synthesised via hybriding the H3R ...
Mingxia Song +5 more
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Antiepileptic Drug Discovery and Development: What Have We Learned and Where Are We Going?
Pharmaceuticals, 2010 Current marketed antiepileptic drugs (AEDs) consist of a variety of structural classes with different mechanisms of action. These agents typically have non-overlapping efficacy and side-effect profiles presenting multiple treatment options for the ...
Jeffrey L. Krajewski, Aaron C. Gerlach
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The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice
Molecules, 2019 Epilepsy is a prevalent neurological disorder that was reported to affect about 56 million people in the world. Approximately one-third of the epileptic patients that suffer from seizures do not receive effective medical treatment.
Xiao Zhang +8 more
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Vitamin D status among children and adolescents on anticonvulsant drugs in southern Switzerland. [PDF]
, 2014 INTRODUCTION It is recognised that vitamin D status is often inadequate (
Bianchetti, Mario Giovanni +6 more
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Molecules, 2015 A novel series of benzenesulfonamide derivatives containing 4-aminobenzenesul-fonamide and α-amides branched valproic acid or 2,2-dimethylcyclopropanecarboxylic acid moieties were synthesized and screened for their anticonvulsant activities in mice ...
Zhiming Wang +5 more
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Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function [PDF]
, 2016 The hypothesis that chronic feeding of the triglycerides of octanoate (trioctanoin) and decanoate (tridecanoin) in "a regular non-ketogenic diet" is anticonvulsant was tested and possible mechanisms of actions were subsequently investigated.
Carrasco-Pozo, Catalina +5 more
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