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Effect of Immunotherapy on Seizure Outcome in Patients with Autoimmune Encephalitis: A Prospective Observational Registry Study. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVE:To evaluate the seizure characteristics and outcome after immunotherapy in adult patients with autoimmune encephalitis (AE) and new-onset seizure.
Jung-Ick Byun   +28 more
doaj   +1 more source

Neural Activity Correlates With Behavior Effects of Anti-Seizure Drugs Efficacy Using the Zebrafish Pentylenetetrazol Seizure Model

open access: yesFrontiers in Pharmacology, 2022
Approximately 30% of patients with epilepsy do not achieve adequate seizure control through current anti-seizure drugs and treatment methods. Therefore, a critical need exists to efficiently screen anti-seizure drugs to enhance our ability to tailor ...
Patrick C. Milder   +3 more
doaj   +1 more source

Discontinuation of preventive antiepileptic drugs in patients with intracerebral hemorrhage

open access: yesBMC Neurology, 2021
Background The risk factors for seizures in patients with intracerebral hemorrhage (ICH) stroke and the effect of seizure prevention by anticonvulsant are not well understood.
Yi-Sin Wong, Chi-Shun Wu, Cheung-Ter Ong
doaj   +1 more source

Neonatal seizures [PDF]

open access: yesAnnals of Neurology, 2007
AbstractIn childhood, the risk for seizures is greatest in the neonatal period. Currently used therapies have limited efficacy. Although the treatment of neonatal seizures has not significantly changed in the past several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generation and ...
Silverstein, Faye Sarah   +1 more
openaire   +3 more sources

On seizure semiology [PDF]

open access: yesEpilepsia, 2021
AbstractThe clinical expression of seizures represents the main symptomatic burden of epilepsy. Neural mechanisms of semiologic production in epilepsy, especially for complex behaviors, remain poorly known. In a framework of epilepsy as a network rather than as a focal disorder, we can think of semiology as being dynamically produced by a set of ...
Mcgonigal, Aileen   +2 more
openaire   +4 more sources

Febrile Seizure [PDF]

open access: yesJournal of Education and Teaching in Emergency Medicine, 2009
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Dubé, CM, Baram, TZ
openaire   +4 more sources

Effect of Ivermectin Treatment on the Frequency of Seizures in Persons with Epilepsy Infected with Onchocerca volvulus

open access: yesPathogens, 2020
A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that ivermectin reduces the seizure frequency. We assessed the effect
Alfred Dusabimana   +9 more
doaj   +1 more source

Raster plots machine learning to predict the seizure liability of drugs and to identify drugs

open access: yesScientific Reports, 2022
In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict
N. Matsuda   +5 more
doaj   +1 more source

An update on the seizures beget seizures theory

open access: yesEpilepsia, 2023
AbstractSeizures beget seizures is a longstanding theory that proposed that seizure activity can impact the structural and functional properties of the brain circuits in ways that contribute to epilepsy progression and the future occurrence of seizures. Originally proposed by Gowers, this theory continues to be quoted in the pathophysiology of epilepsy.
Premysl Jiruska   +3 more
openaire   +3 more sources

Seizure forecasting and cyclic control of seizures [PDF]

open access: yesEpilepsia, 2020
AbstractEpilepsy is a unique neurologic condition characterized by recurrent seizures, where causes, underlying biomarkers, triggers, and patterns differ across individuals. The unpredictability of seizures can heighten fear and anxiety in people with epilepsy, making it difficult to take part in day‐to‐day activities.
Stirling, RE   +3 more
openaire   +3 more sources

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