Results 1 to 10 of about 370,164 (308)
Effect of Immunotherapy on Seizure Outcome in Patients with Autoimmune Encephalitis: A Prospective Observational Registry Study. [PDF]
OBJECTIVE:To evaluate the seizure characteristics and outcome after immunotherapy in adult patients with autoimmune encephalitis (AE) and new-onset seizure.
Jung-Ick Byun +28 more
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Approximately 30% of patients with epilepsy do not achieve adequate seizure control through current anti-seizure drugs and treatment methods. Therefore, a critical need exists to efficiently screen anti-seizure drugs to enhance our ability to tailor ...
Patrick C. Milder +3 more
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Discontinuation of preventive antiepileptic drugs in patients with intracerebral hemorrhage
Background The risk factors for seizures in patients with intracerebral hemorrhage (ICH) stroke and the effect of seizure prevention by anticonvulsant are not well understood.
Yi-Sin Wong, Chi-Shun Wu, Cheung-Ter Ong
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AbstractIn childhood, the risk for seizures is greatest in the neonatal period. Currently used therapies have limited efficacy. Although the treatment of neonatal seizures has not significantly changed in the past several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generation and ...
Silverstein, Faye Sarah +1 more
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AbstractThe clinical expression of seizures represents the main symptomatic burden of epilepsy. Neural mechanisms of semiologic production in epilepsy, especially for complex behaviors, remain poorly known. In a framework of epilepsy as a network rather than as a focal disorder, we can think of semiology as being dynamically produced by a set of ...
Mcgonigal, Aileen +2 more
openaire +4 more sources
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Dubé, CM, Baram, TZ
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A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that ivermectin reduces the seizure frequency. We assessed the effect
Alfred Dusabimana +9 more
doaj +1 more source
Raster plots machine learning to predict the seizure liability of drugs and to identify drugs
In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict
N. Matsuda +5 more
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An update on the seizures beget seizures theory
AbstractSeizures beget seizures is a longstanding theory that proposed that seizure activity can impact the structural and functional properties of the brain circuits in ways that contribute to epilepsy progression and the future occurrence of seizures. Originally proposed by Gowers, this theory continues to be quoted in the pathophysiology of epilepsy.
Premysl Jiruska +3 more
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Seizure forecasting and cyclic control of seizures [PDF]
AbstractEpilepsy is a unique neurologic condition characterized by recurrent seizures, where causes, underlying biomarkers, triggers, and patterns differ across individuals. The unpredictability of seizures can heighten fear and anxiety in people with epilepsy, making it difficult to take part in day‐to‐day activities.
Stirling, RE +3 more
openaire +3 more sources

