Results 31 to 40 of about 370,164 (308)

Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model

Neural Plasticity, 2014
Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons.
Shuzhen Kong, Zhihua Cheng, Jianhui Liu, Yun Wang   +3 more
doaj   +1 more source

Evaluating Therapeutic Equivalence of Generic and Original Levetiracetam in Patients with Epilepsy: A Retrospective Study

Neurology International, 2022
The brand interchangeability of antiepileptic drugs (AEDs) is a topic of debate, especially regarding their therapeutic equivalence. This study evaluates the efficacy and tolerability of generic levetiracetam compared to the brand-name equivalent in a ...
Jannapas Tharavichitkun, Tinonkorn Yadee, Poomchai Angkaow, Thanarat Suansanae   +3 more
doaj   +1 more source

Demonstration project on epilepsy in Brazil: outcome assessment Projeto demonstrativo em epilepsia no Brasil: avaliação do desfecho

Arquivos de Neuro-Psiquiatria, 2007
PURPOSE: To assess the outcome of patients with epilepsy treated at primary care health units under the framework of the demonstration project on epilepsy in Brazil, part of the WHO/ILAE/IBE Global Campaign Against Epilepsy.
Li M. Li, Paula T. Fernandes, Ana L.A. Noronha, Lucia H.N. Marques, Moacir A. Borges, Karina Borges, Fernando Cendes, Carlos A.M. Guerreiro, Dirce M.T. Zanetta, Hanneke M. de Boer, Javier Espíndola, Claudio T. Miranda, Leonid Prilipko, Josemir W. Sander   +13 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity [PDF]

, 2010
Gap junctions within the cerebral cortex may facilitate cortical seizure formation by their ability to synchronize electrical activity. To investigate this, one option is to compare wild-type (WT) animals with those lacking the gene for connexin36 (Cx36 ...
Melin, Sofia M., Jacobson, Gregory M., Voss, Logan J., Sleigh, James W,, Sleigh, James W., Gregory Jacobson, James W. Sleigh, Jacobson, Gregory,, Sofia Melin, Voss, Logan J,, Melin, Sofia,, Logan J. Voss   +11 more
core   +1 more source

Rapid Rescue Treatment with Diazepam Nasal Spray Leads to Faster Seizure Cluster Termination in Epilepsy: An Exploratory Post Hoc Cohort Analysis

Neurology and Therapy
Introduction Although prompt treatment of status epilepticus is standard of care, the effect of timing of rescue therapy administration for seizure clusters in epilepsy remains unknown.
Sunita N. Misra, Randa Jarrar, John M. Stern, Danielle A. Becker, Enrique Carrazana, Adrian L. Rabinowicz   +5 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Topographic distribution of seizure patterns in patients with absence epilepsy [PDF]

, 2010
Background: Absence seizures, which are also known as petit mal seizures, are the most common type of seizures in pediatric epilepsy. They appear in several types of epilepsy and are characterized by impaired consciousness and 3-Hz spike-and-slow-wave ...
Mazzaretto, Andrea
core  

The association between periodontal disease and seizure severity in refractory epilepsy patients

, 2015
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Purpose: Periodontal diseases are common in most populations and affect people at all socioeconomic levels.
Yasuda, CL, Costa, ALF, Nahas-Scocate, ACR, Shibasaki, W, Cendes, F, Carvalho, PEG, de Freitas, CF   +6 more
core   +2 more sources