Results 21 to 30 of about 276,361 (170)

Risk of Seizure Recurrence after First Seizure

Pediatric Neurology Briefs, 1990
The frequency of seizure recurrence in 283 children presenting with a first unprovoked seizure was studied in the Montefiore/Einstein Epilepsy Management Center, Bronx, NY; Yale University School of Medicine, New Haven, CN; and Columbia College of ...
J Gordon Millichap
doaj   +1 more source

Predictive Factors of Seizures in Patients with Organophosphate Poisoning

مجله دانشکده پزشکی اصفهان, 2018
Background: Poisoning with organophosphate (OP) compounds is common and causes many complications, including seizure. The purpose of this study was to investigate the predictor factors of seizure in patients with organophosphate poisoning. Methods: This
Ahmad Yaraghi, Shadi Nasr-Esfahani, Nastaran Eizadi-Mood   +2 more
doaj   +1 more source

Diagnostic role of serum prolactin level in different kinds of seizure and seizure-like episode in children: A hospital-based study

Asian Journal of Medical Sciences
Background: Serum prolactin level has been previously used in distinguishing epileptic seizure from non-epileptic seizure, as prolactin level usually rises following an epileptic seizure in children.
Priyanka Kumari , Sudipto Paul , Moshihur Rahaman Sk, Sumanta Laha , Saikat Mondal , Aditya Kayal   +5 more
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Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model

Neural Plasticity, 2014
Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons.
Shuzhen Kong, Zhihua Cheng, Jianhui Liu, Yun Wang   +3 more
doaj   +1 more source

The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study

Epilepsia Open, 2023
Objective We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin‐dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)]
Mahdi Malekpour, Seyed Reza Salarikia, Mohammad Kashkooli, Ali A. Asadi‐Pooya   +3 more
doaj   +1 more source

Severe isolated sulfide oxidase deficiency with a novel mutation

The Turkish Journal of Pediatrics, 2021
Background. Isolated sulfite oxidase deficiency (ISOD), caused by mutations in SUOX gene, is an autosomal recessive disease manifesting with early onset seizures, developmental delay, microcephaly, and spasticity.
Meriç Ergene, Nuriye Yarar, Elif Perihan Öncel, Taner Sezer, Büşranur Çavdarlı, İsmail Zafer Ecevit, Halil İbrahim Aydın   +6 more
doaj   +1 more source

Rapid Rescue Treatment with Diazepam Nasal Spray Leads to Faster Seizure Cluster Termination in Epilepsy: An Exploratory Post Hoc Cohort Analysis

Neurology and Therapy
Introduction Although prompt treatment of status epilepticus is standard of care, the effect of timing of rescue therapy administration for seizure clusters in epilepsy remains unknown.
Sunita N. Misra, Randa Jarrar, John M. Stern, Danielle A. Becker, Enrique Carrazana, Adrian L. Rabinowicz   +5 more
doaj   +1 more source

FKBP5 blockade may provide a new horizon for the treatment of stress‐associated disorders: An in‐silico study

Epilepsia Open, 2023
Objective We searched for, from the FDA (Food and Drug Administration‐USA)‐approved drugs, inhibitors of FKBP5 with tolerable adverse effect profiles (eg, mild headache, sedation, etc.) and with the ability to cross the blood brain barrier (BBB), using ...
Ali A. Asadi‐Pooya, Mahdi Malekpour, Bardia Zamiri, Mohammad Kashkooli, Negar Firouzabadi   +4 more
doaj   +1 more source

Neuronal-Specific Inhibition of Endoplasmic Reticulum Mg²⁺/Ca²⁺ ATPase Ca²⁺ Uptake in a Mixed Primary Hippocampal Culture Model of Status Epilepticus

Brain Sciences, 2020
Loss of intracellular calcium homeostasis is an established mechanism associated with neuronal dysfunction and status epilepticus. Sequestration of free cytosolic calcium into endoplasmic reticulum by Mg2+/Ca2+ adenosinetriphosphatase (ATPase) is ...
Laxmikant S. Deshpande, Robert J. DeLorenzo, Severn B. Churn, J. Travis Parsons   +3 more
doaj   +1 more source

Diffusion Tensor Imaging and Quantitative Magnetic Resonance Volumetric Assessment in the Diagnosis of Hemimegalencephaly: A Case Report

대한영상의학회지, 2019
A 27-year-old female presented with repeated seizures. As the left frontal lobe volume was enlarged in comparison with the right frontal lobe, hemimegalencephaly was suggested.
Seung-Jin Yoo, Ji Young Lee, Young-Jun Lee, Dong Woo Park, Tae-Yoon Kim, Hee-Jin Kim   +5 more
doaj   +1 more source