EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line [PDF]
BackgroundTransient receptor potential (TRP) channels have been found to have significant implications in neuronal outgrowth, survival, inflammatory neurogenic pain, and various epileptogenic processes.
Ishak Suat Ovey +7 more
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Effects of single-dose neuropeptide Y on levels of hippocampal BDNF, MDA, GSH, and NO in a rat model of pentylenetetrazole-induced epileptic seizure [PDF]
Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, which may increase the content of reactive oxygen and nitrogen species.
Hale Maral Kir +4 more
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The purpose of this study was to investigate the effect of hydroalcoholic extract of Artemisia persica (100, 200 and 400 mg/kg) on pentylenetetrazole-induced seizure and memory impairment. Sixty mice were assigned to seven groups.
Mozhgan Daneshkhah, Mahbubeh Setorki
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Effect of Deep Brain Stimulation in The Ventral Tegmental Area on Neuronal Activity in Local and Remote Brain Regions in Kindled Mice [PDF]
Objective: The mechanisms behind seizure suppression by deep brain stimulation (DBS) are not fully revealed, andthe most optimal stimulus regimens and anatomical targets are yet to be determined. We investigated the modulatoryeffect of low-frequency DBS (
Parisa Esmaeili Tazangi +5 more
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Effects of Hydro-ethanolic Extract of Tanacetum parthenium and its N-Butanol and Aqueous Fractions on Brain Oxidative Damage in Pentylenetetrazole-Induced Seizures in Mice [PDF]
Background: Epileptic seizures affect the life of noticeable number of people in all over the world. Tanacetum parthenium (TP) is used in traditional medicine.
Fereshteh Asgharzadeh +8 more
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Effects of different anesthetic agents on GM-CSF, MCP1, IL1α and TNFα levels in rat sepsis model [PDF]
Anesthetic agents could alter the course and outcome of physical trauma, as well as experimentally or naturally occurring severe infections, by regulating several immune response mechanisms.
Vojvodić Danilo +7 more
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Approximately 30% of epileptic patients develop Drug-Resistant Epilepsy. Based on evidence that shows a loss of efficacy in some sodium channel blocker antiseizure drugs in epilepsy, we focus our study on assessing the anticonvulsant efficacy of ...
Cecilia Zavala-Tecuapetla +3 more
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Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement [PDF]
Background: Edaravone is an anti-stroke medication that may have nitric oxide (NO) modulating properties. This study evaluated the role of NO in the acute and sub-chronic anticonvulsant effects of edaravone in murine models of seizures induced by ...
Leila Moezi +5 more
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Influence of NG-nitro-L-arginine methyl ester on clinical and biochemical effects of methylene blue in pentylenetetrazole-evoked convulsions [PDF]
Background/Aim. Despite years of research in a number of experimental models the question whether nitric oxide (NO) and methylene blue (MB) have pro- or anticonvulsant effects remains to be fully resolved. Methods.
Jelenković Ankica +4 more
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The Effect of Hydroalcoholic Extract of Salep on Pentylenetetrazole-Induced Seizure in Adult Male Rats [PDF]
Background and Aim: Epilepsy as a neurological disorder is characterized by unpredictable and periodic seizures. In the present study, the anticonvulsant effect of different doses of salep hydroalcoholic extract on pentylenetetrazole (PTZ) induced ...
Hossein Kargar Jahromi +7 more
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