Results 11 to 20 of about 4,421 (183)
Effects of different anesthetic agents on GM-CSF, MCP1, IL1α and TNFα levels in rat sepsis model [PDF]
Anesthetic agents could alter the course and outcome of physical trauma, as well as experimentally or naturally occurring severe infections, by regulating several immune response mechanisms.
Vojvodić Danilo +7 more
doaj +1 more source
Approximately 30% of epileptic patients develop Drug-Resistant Epilepsy. Based on evidence that shows a loss of efficacy in some sodium channel blocker antiseizure drugs in epilepsy, we focus our study on assessing the anticonvulsant efficacy of ...
Cecilia Zavala-Tecuapetla +3 more
doaj +1 more source
Influence of NG-nitro-L-arginine methyl ester on clinical and biochemical effects of methylene blue in pentylenetetrazole-evoked convulsions [PDF]
Background/Aim. Despite years of research in a number of experimental models the question whether nitric oxide (NO) and methylene blue (MB) have pro- or anticonvulsant effects remains to be fully resolved. Methods.
Jelenković Ankica +4 more
doaj +1 more source
Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, which may increase the content of reactive oxygen and nitrogen species.
Hale Maral Kir +4 more
doaj +1 more source
The Effect of Hydroalcoholic Extract of Salep on Pentylenetetrazole-Induced Seizure in Adult Male Rats [PDF]
Background and Aim: Epilepsy as a neurological disorder is characterized by unpredictable and periodic seizures. In the present study, the anticonvulsant effect of different doses of salep hydroalcoholic extract on pentylenetetrazole (PTZ) induced ...
Hossein Kargar Jahromi +7 more
doaj
Effects of L-carnitine and Ginkgo bilobaon cerebral cortex in experimentally-induced epileptic seizures disease in rat [PDF]
Pentylenetetrazole (PTZ) kindling is an acknowledged model for epilepsy and refers to a phenomenon in which repeated injection of this drug causes a gradual seizure. The current study aimed to determine the possible protective and ameliorative effects of
Ehab Tousson +2 more
doaj +1 more source
Reverse transcription followed by quantitative polymerase chain reaction (qRT-PCR) is a powerful and commonly used tool for gene expression analysis. It requires the right choice of stably expressed reference genes for accurate normalization.
Alexander P. Schwarz +5 more
doaj +1 more source
Palmatine (PALM) and berberine (BERB) are widely identified isoquinoline alkaloids among the representatives of the Berberidaceae botanical family. The antiseizure activity of BERB was shown previously in experimental epilepsy models.
Kinga Gawel +8 more
doaj +1 more source
The Anxiolytic and Antidepressant Effect of Tanacetum polycephalum in the Pentylenetetrazole Kindled Rats [PDF]
Background and objective: Epilepsy one the most prevalent neurological illness which affects behavioral statuses like anxiety, depression and balance.
Vahid Azizi +3 more
doaj +1 more source
Anethole exerted anticonvulsant effect in pentylenetetrazolemodel of seizure in male mice: Possible antioxidant effects [PDF]
Background and aims: Epilepsy is a neurological disorder causing brain dysfunctions. Treatment and control of epilepsy have long been a challenge in medical sciences. Despite the variety of current anticonvulsant drugs, research continues to discover new
Sanaz Salimian +4 more
doaj +1 more source

