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Antinociceptive and anti-inflammatory effect of a standardized fraction of Oenothera rosea L'Hér. ex Aiton and its possible mechanism of action in mice [PDF]
Avicenna Journal of Phytomedicine, 2022 Objective: This study was conducted to investigate the antinociceptive and anti-inflammatory effect of ethyl acetate fraction of Oenothera rosea (EAOr) and the mechanism involved, in mice.Materials and Methods: The antinociceptive activity was tested ...
Rodrigo Vargas-Ruiz +6 more
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Psychobiotics – Probiotics that Improve Mood
Harčova Nauka ì Tehnologìâ, 2021 The human intestinal microbiome includes all microorganisms inhabiting the intestinal tract. One study showed that mice raised in a sterile environment exhibited excessive physiological responses to stress compared to normal control.
L. Kapreliants, E Zhuk
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Shipin gongye ke-ji, 2023 Objective: To study the sleep-improving effect of Ziziphi spinosae Semen Poria cocos powder and soybean peptide powder on insomnia model mice induced by p-chlorophenylalanine (PCPA). Methods: One hundred eighty SPF male BALB/c mice were purchased. First,
Rong WEI +4 more
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WormBook, 2005 The most abundant synapses in the central nervous system of vertebrates are inhibitory synapses that use the neurotransmitter gamma-aminobutyric acid (GABA). GABA is also an important neurotransmitter in C. elegans; however, in contrast to vertebrates where GABA acts at synapses of the central nervous system, in nematodes GABA acts primarily at ...
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Open Life Sciences, 2023 In addition to the known metabolic alterations, obesity has consequences at the brain level, driving imbalance in neurotransmitters such as glutamate (Glu), glutamine (Gln), and gamma-aminobutyric acid (GABA).
Sandoval-Salazar Cuauhtémoc +4 more
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Frontiers in Immunology, 2022 Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act to inhibit their inflammatory activities, and 2) lung ...
Jide Tian +4 more
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Indian Journal of Neurosurgery, 2013 Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee +2 more
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Gamma-hydroxybutyrate abuse: pharmacology and poisoning and withdrawal management
Arhiv za Higijenu Rada i Toksikologiju, 2020 Gamma-hydroxybutyrate (GHB) is a central nervous system depressant primarily used as a recreational drug of abuse, but also for the treatment of narcolepsy with cataplexy in adult patients and as an adjuvant for control of alcohol withdrawal syndrome ...
Marinelli Enrico +4 more
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Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice
Journal of Integrative Neuroscience, 2023 Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system.
Qais Jarrar +8 more
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Disease Models & Mechanisms, 2019 Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from excessive, hypersynchronous brain activity ...
Meijiang Liao +7 more
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