Results 21 to 30 of about 159,634 (258)

Targeted knockout of GABA-A receptor gamma 2 subunit provokes transient light-induced reflex seizures in zebrafish larvae

open access: yesDisease Models & Mechanisms, 2019
Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from excessive, hypersynchronous brain activity ...
Meijiang Liao   +7 more
doaj   +1 more source

Mesencephalic GABA neuronal development: no more on the other side of oblivion

open access: yesBiomolecular Concepts, 2014
Midbrain GABA neurons, endowed with multiple morphological, physiological and molecular characteristics as well as projection patterns are key players interacting with diverse regions of the brain and capable of modulating several aspects of behavior ...
Li Suyan, Joshee Sampada, Vasudevan Anju
doaj   +1 more source

Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus

open access: yesPharmaceuticals, 2019
Lurasidone is an atypical mood-stabilizing antipsychotic agent with unique receptor-binding profile, including 5-HT7 receptor (5-HT7R) antagonism. Effects of 5-HT7R antagonism on transmitter systems of schizophrenia and mood disorders, however, have not ...
Motohiro Okada   +4 more
doaj   +1 more source

Extrasynaptic δ-subunit containing GABAA receptors [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
γ-Aminobutyric acid type A receptors (GABAARs) are GABA gated heteropentameric chloride channels responsible for the adult brain’s primary inhibition.
Ayla Arslan
doaj   +1 more source

Investigation on Hypothalamic GABAergic system difference of local and Leghorn hens based on RNA-Seq dataset [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2023
Objective: g-Aminobutyric acid (GABA) is a non-protein amino acid synthesized by decarboxylation of glutamate by the enzyme glutamic acid decarboxylase. The central nervous system (CNS) contains uniquely high concentrations of GABA, and GABA serves as a ...
Yadollah Badakhshan   +2 more
doaj   +1 more source

sleep disorders due to neuroinfections: clinical symptoms, neurochemistry and neurophysiology V.B. Voitenkov1, N.V. Skripchenko1, Y.E. Zueva 2

open access: yesЖурнал инфектологии, 2015
In our review we present data on sleep disturbances in neuroinfections (encephalitis and meningitis), their clinical signs, neurochemistry and neurophysiology.
V. B. Voitenkov   +2 more
doaj   +1 more source

Psychotic Episodes After Vigabatrine Treatment: A Case Report

open access: yesPsychiatry and Behavioral Sciences, 2020
Vigabatrin is an antiepileptic that functions by increasing ɣ-aminobutyric acid (GABA) levels in the brain. Like other antiepileptics, it also causes neuropsychiatric side effects. Among these side effects, psychosis draws particular attention. Drug-
Erdem Uysal   +2 more
doaj   +1 more source

Investigation of the Effect of Anakinra on Pentylenetetrazole-Induced Epileptic Seizures in Mice

open access: yesAhi Evran Medical Journal, 2021
Purpose: Disruption of the balance between gamma aminobutyric acid (GABA) and glutamate in the brain is one of the important factors contributing to seizure formation and epileptogenesis.
Ahmet Kemal FİLİZ   +1 more
doaj   +1 more source

Chasing after minerality, relationship to yeasts nutritional stress and succinic acid production

open access: yesCzech Journal of Food Sciences, 2012
Minerality is certainly one of the most mysterious and most valuable tones of wine taste and it is very often associated with the concept of terroir. The isotachophoresis was used for determination of cations - minerals in two wines from vineyards with ...
Mojmír Baroň, Jaromír Fiala
doaj   +1 more source

Morpho-physiological Diversity of Cholecystokinin-expressing Interneurons in the Dentate Gyrus

open access: yesJournal of Physiological Investigation
The hippocampus plays a crucial role in learning, memory, and emotion, with the dentate gyrus (DG) serving as the primary gateway. The DG receives multimodal sensory inputs from outside the hippocampus and relays this integrated information to downstream
Yu-Jui Li   +4 more
doaj   +1 more source

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