Results 11 to 20 of about 159,634 (258)

Antinociceptive and anti-inflammatory effect of a standardized fraction of Oenothera rosea L'Hér. ex Aiton and its possible mechanism of action in mice [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2022
Objective: This study was conducted to investigate the antinociceptive and anti-inflammatory effect of ethyl acetate fraction of Oenothera rosea (EAOr) and the mechanism involved, in mice.Materials and Methods: The antinociceptive activity was tested ...
Rodrigo Vargas-Ruiz   +6 more
doaj   +1 more source

Psychobiotics – Probiotics that Improve Mood

open access: yesHarčova Nauka ì Tehnologìâ, 2021
The human intestinal microbiome includes all microorganisms inhabiting the intestinal tract. One study showed that mice raised in a sterile environment exhibited excessive physiological responses to stress compared to normal control.
L. Kapreliants, E Zhuk
doaj   +1 more source

Study on the Effect of Ziziphi spinosae Semen Poria cocos Powder and Soybean Peptide Powder on Improving Sleep in Insomnia Model Mice

open access: yesShipin gongye ke-ji, 2023
Objective: To study the sleep-improving effect of Ziziphi spinosae Semen Poria cocos powder and soybean peptide powder on insomnia model mice induced by p-chlorophenylalanine (PCPA). Methods: One hundred eighty SPF male BALB/c mice were purchased. First,
Rong WEI   +4 more
doaj   +1 more source

Effect of berrycactus fruit (Myrtillocactus geometrizans) on glutamate, glutamine, and GABA levels in the frontal cortex of rats fed with a high-fat diet

open access: yesOpen Life Sciences, 2023
In addition to the known metabolic alterations, obesity has consequences at the brain level, driving imbalance in neurotransmitters such as glutamate (Glu), glutamine (Gln), and gamma-aminobutyric acid (GABA).
Sandoval-Salazar Cuauhtémoc   +4 more
doaj   +1 more source

GABA [PDF]

open access: yesWormBook, 2005
The most abundant synapses in the central nervous system of vertebrates are inhibitory synapses that use the neurotransmitter gamma-aminobutyric acid (GABA). GABA is also an important neurotransmitter in C. elegans; however, in contrast to vertebrates where GABA acts at synapses of the central nervous system, in nematodes GABA acts primarily at ...
openaire   +3 more sources

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

open access: yesFrontiers in Immunology, 2022
Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act to inhibit their inflammatory activities, and 2) lung ...
Jide Tian   +4 more
doaj   +1 more source

Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

open access: yesIndian Journal of Neurosurgery, 2013
Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee   +2 more
doaj   +1 more source

Aging and GABA

open access: yesAging, 2018
sponsorship: This work was supported by the Research Fund KU Leuven (C16/15/070) and the Research Foundation Flanders (FWO) grant (G089818N) and Excellence of Science grant (EOS 30446199, MEMODYN) awarded to SPS. CM is funded by an aspirant fellowship of the Research Foundation Flanders (FWO).
Cuypers, Koen   +2 more
openaire   +3 more sources

Gamma-hydroxybutyrate abuse: pharmacology and poisoning and withdrawal management

open access: yesArhiv za Higijenu Rada i Toksikologiju, 2020
Gamma-hydroxybutyrate (GHB) is a central nervous system depressant primarily used as a recreational drug of abuse, but also for the treatment of narcolepsy with cataplexy in adult patients and as an adjuvant for control of alcohol withdrawal syndrome ...
Marinelli Enrico   +4 more
doaj   +1 more source

Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice

open access: yesJournal of Integrative Neuroscience, 2023
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system.
Qais Jarrar   +8 more
doaj   +1 more source

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