Results 31 to 40 of about 159,869 (159)

Enhanced inhibitory effects of GABA on renal and hepatic function, molecular profiles, and histological changes in male albino mice

Open Veterinary Journal
Background: The gamma-aminobutyric acid GABA receptors are considered the main inhibitory neurotransmitter receptors in mammalian brain and they have been proved to be existing in non-neuronal cells. Aim: Lorazepam which is one of the benzodiazepines,
Mohammed Abdullah Ajeel, Israa A. Al-Robaiee   +1 more
doaj   +1 more source

Phenotype Expression Variability in Children with GABRB3 Heterozygous Mutations

Oman Medical Journal, 2021
GABRB3 gene is a recently identified gene located in 15q12 chromosome and encodes for gamma-aminobutyric acid (GABA) receptor subunit beta-3 protein, which is linked to the GABAA receptor.
Abdulhafeez M. Khair, Alana E. Salvucci
doaj   +1 more source

Astrocyte-Ablation of Mtnr1b Increases Anxiety-Like Behavior in Adult Male Mice

Journal of Integrative Neuroscience, 2023
Background: Astrocytes are essential for synaptic transmission, and their dysfunction can result in neuropsychiatric disorders such as anxiety and depression.
Zijun Meng, Shipeng Guo, Xiangjun Dong, Qunxian Wang, Dongjie Hu, Xiaoqi Liu, Yanshuang Jiang, Liangye Ji, Jie Zhang, Weiyi Zhu, Weihui Zhou, Weihong Song   +11 more
doaj   +1 more source

Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

Acta Pharmaceutica, 2018
In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated.
Vega Rasgado Lourdes A., Reyes Guillermo Ceballos, Vega Díaz Fernando   +2 more
doaj   +1 more source

Identification of Novel Prognostic Biomarkers That are Associated with Immune Microenvironment Based on GABA-Related Molecular Subtypes in Gastric Cancer

Pharmacogenomics and Personalized Medicine, 2023
Beibei Wang, Linlin Huang, Shanliang Ye, Zhongwen Zheng, Shanying Liao Department of Gastroenterology and Hepatology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, People’s Republic of ...
Wang B, Huang L, Ye S, Zheng Z, Liao S
doaj  

Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons

eLife, 2020
In violation of Dale’s principle several neuronal subtypes utilize more than one classical neurotransmitter. Molecular identification of vesicular glutamate transporter three and cholecystokinin expressing cortical interneurons (CCK+VGluT3+INTs) has ...
Kenneth A Pelkey, Daniela Calvigioni, Calvin Fang, Geoffrey Vargish, Tyler Ekins, Kurt Auville, Jason C Wester, Mandy Lai, Connie Mackenzie-Gray Scott, Xiaoqing Yuan, Steven Hunt, Daniel Abebe, Qing Xu, Jordane Dimidschstein, Gordon Fishell, Ramesh Chittajallu, Chris J McBain   +16 more
doaj   +1 more source

L-655,708 does not prevent isoflurane-induced memory deficits in old mice

Translational Neuroscience, 2019
General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD). Effective agents for the prevention or treatment of POCD are urgently needed.
Gao Teng, Liu Yue, Zhao Zifang, Luo Yuan, Wang Lifang, Wang Yongan, Yin Yiqing   +6 more
doaj   +1 more source

Modelo in vitro para el estudio del papel de la unión mesopontina en la generación del sueño de movimientos oculares rápidos y la vigilia

Anales de la Facultad de Medicina, 2016
El estudio de las estrategias neurales para la organización del comportamiento en vertebrados constituye un desafío mayor para la Neurociencia. El avance del conocimiento en este campo depende de manera crítica de la utilización de modelos experimentales
Esteban Pino, Héctor Kunizawa, Jack Yamuy, Michel Borde   +3 more
doaj   +1 more source

Cerebellar Purkinje Cells and GABA Neurotransmission in the Diabetic Rodent Models: A Systematic Review

Aksona
Highlight: • Reduced cerebellar Purkinje cell numbers and altered dendritic trees due to cell deaths were reported in hyperglycemia. •  In hyperglycemia, altered GABAergic neurotransmissions are due to lower GABA synthesis and its receptors expression
Viskasari P Kalanjati, Rayhan B Mahdi, Dwi Martha Nur Aditya   +2 more
doaj   +1 more source

Effect of germination on main physiology and biochemistry metabolism of sorghum seeds

Bioscience Journal, 2016
The main physiology and biochemistry metabolism including amino acids composition and gamma-aminobutyric acid (GABA) content of sorghum during 3-day germination period was investigated. Respiratory rate increased during germination.
Runqiang Yang, Peng Wang, Maha F. Elbaloula, Zhenxin Gu   +3 more
doaj   +1 more source