Results 31 to 40 of about 219,640 (255)

Phenotype Expression Variability in Children with GABRB3 Heterozygous Mutations

open access: yesOman Medical Journal, 2021
GABRB3 gene is a recently identified gene located in 15q12 chromosome and encodes for gamma-aminobutyric acid (GABA) receptor subunit beta-3 protein, which is linked to the GABAA receptor.
Abdulhafeez M. Khair, Alana E. Salvucci
doaj   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

open access: yes, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas   +7 more
core   +1 more source

Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

open access: yesActa Pharmaceutica, 2018
In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated.
Vega Rasgado Lourdes A.   +2 more
doaj   +1 more source

Astrocyte-Ablation of Mtnr1b Increases Anxiety-Like Behavior in Adult Male Mice

open access: yesJournal of Integrative Neuroscience, 2023
Background: Astrocytes are essential for synaptic transmission, and their dysfunction can result in neuropsychiatric disorders such as anxiety and depression.
Zijun Meng   +11 more
doaj   +1 more source

Molecular pharmacology of an insect GABA receptor [PDF]

open access: yes, 2010
Cys-loop receptors are ligand-gated ion channels that are involved in fast synaptic neurotransmission in the central and peripheral nervous system. The Cys-loop receptor RDL (‘resistant to dieldrin’) is a GABA-gated chloride channel from Drosophila ...

core   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Identification of Novel Prognostic Biomarkers That are Associated with Immune Microenvironment Based on GABA-Related Molecular Subtypes in Gastric Cancer

open access: yesPharmacogenomics and Personalized Medicine, 2023
Beibei Wang, Linlin Huang, Shanliang Ye, Zhongwen Zheng, Shanying Liao Department of Gastroenterology and Hepatology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, People’s Republic of ...
Wang B, Huang L, Ye S, Zheng Z, Liao S
doaj  

Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]

open access: yes, 1975
The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J.   +9 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

An intracellular analysis of gamma-aminobutyric-acid-associated ion movements in rat sympathetic neurones [PDF]

open access: yes, 1985
Double-barrelled ion-sensitive micro-electrodes were used to measure the changes of the intracellular activities of Cl-, K+, and Na+ (aiCl, aiK, aiNa) in neurones of isolated rat sympathetic ganglia during the action of gamma-aminobutyric acid (GABA ...
Ballanyi, Klaus   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy