Results 11 to 20 of about 78,762 (304)

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

open access: yesFrontiers in Cell and Developmental Biology, 2022
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders.
John W. Steele   +13 more
doaj   +1 more source

Effects Of 4-thiazolidinone Derivatives Les-2658 And Les-1205 On Sleep - Wakefulness Cycle In Kindled Rats [PDF]

open access: yes, 2017
The research is dedicated to in-depth study of neurotrophic and antiepileptic properties of original potential anticonvulsant agents from 4-thiazolidinones – LES-2658 (5-(3-nitro-benzylidene)-2-(thiazol-2-ylimino)-thiazolidin-4-one) and LES-1205 ([2,4 ...
Lesyk, R. (Roman)   +2 more
core   +2 more sources

Recognition Memory After Febrile Seizures

open access: yesPediatric Neurology Briefs, 2012
Researchers at the Institute of Child Health, London; Epilepsy Center, University of Edinburgh; and Dartmouth Medical School, New Hampshire, US studied memory abilities in 26 children (mean age 23 months, SD 12.6 months) after prolonged febrile seizures (
J Gordon Millichap
doaj   +1 more source

Patient Harm Resulting From Medication Reconciliation Process Failures: A Study of Serious Events Reported by Pennsylvania Hospitals

open access: yesPatient Safety, 2021
Medication reconciliation broadly defined includes both formal and informal processes that involve the comprehensive evaluation of a patient’s medications during each transition of care and change in therapy.
Amy Harper   +2 more
doaj   +1 more source

Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

open access: yesEpilepsia Open, 2019
Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf   +5 more
doaj   +1 more source

Continuous rate infusion of midazolam as emergent treatment for seizures in dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE). Objective To describe the use and safety of midazolam CRI in dogs with CS or SE.
Kathryn Y. Bray   +4 more
doaj   +1 more source

Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats [PDF]

open access: yes, 1992
Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress.
Beldhuis, Hans J.A.,   +2 more
core   +2 more sources

The Effects of Valproic Acid on Appetitive and Aversive Instrumental Learning in Adult Rats

open access: yesFrontiers in Behavioral Neuroscience, 2014
Antiepileptic medications are the frontline treatment for seizure conditions. However, these medications are not without cognitive side effects. Previously, our laboratory reported learning deficits in phenytoin and carbamazepine-treated rats.
John Joseph Orczyk   +4 more
doaj   +1 more source

Neuropharmacological Activity of the Acetonic Extract of Malpighia mexicana A. Juss. and Its Phytochemical Profile

open access: yesScientia Pharmaceutica, 2023
Mental and neurological disorders are conditions that affect thoughts, emotions, behavior, and relationships. Malpighia mexicana A. Juss. is a plant used in Mexican traditional medicine for the treatment of such disorders.
Dante Avilés-Montes   +11 more
doaj   +1 more source

Impaired biotin status in anticonvulsant therapy [PDF]

open access: yes, 1982
In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher ...
Bonjour   +7 more
core   +1 more source

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