Results 11 to 20 of about 47,981 (309)

Why inositol supplementation may help to recover side effects induced by mood stabilizers and anticonvulsant drugs [PDF]

open access: yes, 2022
Lithium, valproic acid and carbamazepine are the most used mood stabilizers and anticonvulsant drugs. They share the depletion of myo-inositol in the central nervous system as mechanism of action.
Mario Montanino Oliva   +4 more
core   +1 more source

Sulforaphane is anticonvulsant and improves mitochondrial function [PDF]

open access: yes, 2015
The nuclear factor erythroid 2-related factor 2 pathway (Nrf2) has been previously identified to protect the brain against various impacts. Here, we investigated the effect of the Nrf2 activator sulforaphane in various seizure models and hippocampal ...
Carrasco-Pozo, Catalina   +2 more
core   +1 more source

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

open access: yesFrontiers in Cell and Developmental Biology, 2022
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders.
John W. Steele   +13 more
doaj   +1 more source

What can we learn from clinical trials of anticonvulsant drugs in epilepsy? [PDF]

open access: yes, 2002
Any physician who intends to utilize the available antiepileptic drugs (AEDs) judiciously, cannot do so without being well versed on their pharmacological properties and the large body of evidence that is continuously accumulating on their relative ...
What Can We Learn From Clinical Trials Of Anticonvulsant Drugs In Epilepsy?   +1 more
core   +1 more source

Timing of Anticonvulsant Administration in Status Epilepticus

open access: yesPediatric Neurology Briefs, 2015
Investigators from the Pediatric Status Epilepticus Research Group studied the time elapsed from onset of pediatric convulsive status epilepticus (SE) to administration of antiepileptic drugs (AED).
Juan A Piantino
doaj   +1 more source

Bone mineral density, vitamin D and anticonvulsant therapy [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2000
The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS: Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were ...
SILVANA FILARDI   +3 more
doaj   +1 more source

Patient Harm Resulting From Medication Reconciliation Process Failures: A Study of Serious Events Reported by Pennsylvania Hospitals

open access: yesPatient Safety, 2021
Medication reconciliation broadly defined includes both formal and informal processes that involve the comprehensive evaluation of a patient’s medications during each transition of care and change in therapy.
Amy Harper   +2 more
doaj   +1 more source

Recognition Memory After Febrile Seizures

open access: yesPediatric Neurology Briefs, 2012
Researchers at the Institute of Child Health, London; Epilepsy Center, University of Edinburgh; and Dartmouth Medical School, New Hampshire, US studied memory abilities in 26 children (mean age 23 months, SD 12.6 months) after prolonged febrile seizures (
J Gordon Millichap
doaj   +1 more source

Impaired biotin status in anticonvulsant therapy [PDF]

open access: yes, 1982
In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher ...
Krause, Klaus-Henning   +2 more
core   +1 more source

Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

open access: yesEpilepsia Open, 2019
Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf   +5 more
doaj   +1 more source

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