Results 11 to 20 of about 53,577 (300)

Why inositol supplementation may help to recover side effects induced by mood stabilizers and anticonvulsant drugs [PDF]

open access: yes, 2022
Lithium, valproic acid and carbamazepine are the most used mood stabilizers and anticonvulsant drugs. They share the depletion of myo-inositol in the central nervous system as mechanism of action.
Mario Montanino Oliva   +4 more
core   +1 more source

Anticonvulsants in pregnancy. [PDF]

open access: yesArchives of Disease in Childhood, 1991
Epilepsy and pregnancy Recurrent seizures affect at least 1% of women who are of childbearing age, but as the fertility of both men and women with epilepsy is slightly reduced,' about one in 200 pregnancies occurs in a woman with epilepsy. Most of these women are taking anticonvulsants regularly.
C J, Kilpatrick, R F, Moulds
openaire   +4 more sources

Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler's virus model of temporal lobe epilepsy

open access: yesNeurobiology of Disease, 2014
Viral infection of the CNS can result in encephalitis and acute seizures, increasing the risk for later-life epilepsy. We have previously characterized a novel animal model of temporal lobe epilepsy that recapitulates key sequela in the development of ...
Anthony D. Umpierre   +8 more
doaj   +1 more source

Bromide Dose in Dogs With Epilepsy Living Close to Coastal Areas and Living More Inland: A Retrospective Observational Study

open access: yesFrontiers in Veterinary Science, 2022
Potassium bromide is a frequently used antiseizure medication with a half-life time of over 25 days. Oral intake of sodium chloride as well as renal function influence this half-life time and may have an influence on the needed dose to get proper serum ...
Esther A. Lichtenauer   +4 more
doaj   +1 more source

Anticonvulsant activity of nicardipine in experimentally induced seizures in wistar albino rats. [PDF]

open access: yes, 2020
Background: The objective of the study was to evaluate the anticonvulsant activity of nicardipine in wistar albino rats.Methods: Anticonvulsant activity of nicardipine in a dose 10 mg/kg, and its effect with the standard drug lamotrigine (5 mg/kg) was ...
M. K., Kayalvizhi
core   +1 more source

Design, Synthesis, and Evaluation of Anticonvulsant Activities of New Triazolopyrimidine Derivatives

open access: yesFrontiers in Chemistry, 2022
Epilepsy, a severe brain disease affecting a large population, is treated mainly by antiepileptic drugs (AEDs). However, toxicity, intolerance, and low efficiency of the available AEDs have prompted the continual attempts in the discovery of new AEDs. In
Mingxia Song   +7 more
doaj   +1 more source

Anticonvulsants for fibromyalgia [PDF]

open access: yesCochrane Database of Systematic Reviews, 2013
Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. People often report high disability levels and poor health-related quality of life (HRQoL). Drug therapy focuses on reducing key symptoms and disability, and improving HRQoL.
Nurcan, Üçeyler   +3 more
openaire   +2 more sources

Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

open access: yesEpilepsia Open, 2019
Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf   +5 more
doaj   +1 more source

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

open access: yesMolecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Evaluation of anticonvulsant activity of amlodipine in albino rats [PDF]

open access: yes, 2017
Background: The objective of the study was to evaluate the anticonvulsant activity of amlodipine in albino rats.Methods: Anticonvulsant activity of amlodipine was done in three graded doses (1 mg/kg, 2 mg/kg, 4 mg/kg), and combination group with low dose
M., Janardhan   +5 more
core   +1 more source

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