Results 1 to 10 of about 34,736 (151)

Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug–Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach

Pharmaceutics, 2021
The anticonvulsant carbamazepine is frequently used in the long-term therapy of epilepsy and is a known substrate and inducer of cytochrome P450 (CYP) 3A4 and CYP2B6. Carbamazepine induces the metabolism of various drugs (including its own); on the other
Laura Maria Fuhr, Fatima Zahra Marok, Nina Hanke, Dominik Selzer, Thorsten Lehr   +4 more
doaj   +2 more sources

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +2 more sources

Development of ternary solid dispersions with hydrophilic polymer and surface adsorbent for improving dissolution rate of carbamazepine

Saudi Pharmaceutical Journal, 2018
In this study solid dispersions of carbamazepine in the hydrophilic Kollidon® VA64 polymer, adsorbed onto Neusilin® UFL2 adsorption carrier have been employed to improve carbamazepine dissolution rate.
Tanja Vojinović, Djordje Medarević, Edina Vranić, Zorica Potpara, Marko Krstić, Jelena Djuriš, Svetlana Ibrić   +6 more
doaj   +2 more sources

Carbamazepine

Cogitare Enfermagem
Objective: To describe the profile, associated medications, potential adverse events (AE), anxiety levels, and treatment adherence among carbamazepine (CBZ) users.
Karine Raquel Uhdich Kleibert, Alana Thais Gisch Andres, Lenara Schalanski Krause, Viviane Fereira de Melo, Adriane Cristina Bernat Kolankiewicz, Mariana Rodriges Botton, Christiane de Fátima Colet   +6 more
doaj   +3 more sources

Carbamazepine Induces Platelet Apoptosis and Thrombocytopenia Through Protein Kinase A

Frontiers in Pharmacology, 2021
Carbamazepine is extensively used worldwide to treat a wide range of disorders such as epilepsy, peripheral neuralgia and bipolar disorder. Thrombocytopenia and hemorrhage have been identified in multiple carbamazepine-treated patients.
Weiling Xiao, Weiling Xiao, Kangxi Zhou, Mengnan Yang, Chenglin Sun, Lan Dai, Jian Gu, Rong Yan, Kesheng Dai   +8 more
doaj   +1 more source

The effect of multidrug exposure on neurological manifestations in carbamazepine intoxication: a nested case-control study

BMC Pharmacology and Toxicology, 2020
Background In acute intoxication, carbamazepine concentration above 40 mcg/ml is associated with a risk of severe neurological consequences, including depressed consciousness, respiratory depression, cardiac conduction disorders, seizures, and death ...
Ayala Hirsch, Maor Wanounou, Amichai Perlman, Bruria Hirsh-Raccah, Mordechai Muszkat   +4 more
doaj   +1 more source

Fabrication of Bi4O5Br2 photocatalyst for carbamazepine degradation under visible-light irradiation

Water Science and Technology, 2021
Bi4O5Br2 with irregular flake shape was synthesized by a facile and energy-saving hydrolysis method. Its band gap energy (Eg) was 2.1 eV. The formation mechanism was proposed.
Xiaoming Mao, Min Li, Mengyao Li
doaj   +1 more source

Carbamazepine for schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2014
Many people with schizophrenia do not achieve a satisfactory treatment response with just antipsychotic drug treatment and various adjunct medications are used to promote additional response. The antiepileptic carbamazepine is one such drug.To examine whether carbamazepine or oxcarbazepine alone is an effective treatment for schizophrenia and ...
Stefan, Leucht, Bartosz, Helfer, Markus, Dold, Werner, Kissling, John, McGrath   +4 more
openaire   +2 more sources

Toxicokinetics and correlation of carbamazepine salivary and serum concentrations in acute poisonings [PDF]

Vojnosanitetski Pregled, 2012
Background/Aim. Saliva is a body fluid which, like serum, can be used for determination of concentrations of certain drugs, both in pharmacotherapy as well as in acute poisonings.
Đorđević Snežana, Kilibarda Vesna, Vučinić Slavica, Stojanović Tomislav, Antonijević Biljana   +4 more
doaj   +1 more source

Involuntary human exposure to carbamazepine: A cross-sectional study of correlates across the lifespan and dietary spectrum.

Environment International, 2020
Treated wastewater (TWW) is increasingly used for agricultural irrigation, especially in arid and semi-arid regions. Carbamazepine is among the most frequently detected pharmaceuticals in TWW.
Michael Schapira, O. Manor, Naama Golan, D. Kalo, Vered Mordehay, Noam Kirshenbaum, R. Goldsmith, B. Chefetz, O. Paltiel   +8 more
semanticscholar   +1 more source