Archives of Medical Science, 2016 Introduction : The prescribed dose and carbamazepine plasma concentration to achieve the optimal therapeutic efficacy are highly variable from one patient to the other.
Chahra Chbili +6 more
doaj +2 more sources
Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion [PDF]
Case Reports in Medicine, 2015 Carbamazepine is a widely used anticonvulsant. Its metabolite, carbamazepine-10,11-epoxide, has been found to display similar anticonvulsant and neurotoxic properties. While the ratio of parent to metabolite concentration varies significantly, at therapeutic doses the epoxide concentration is generally about 20% of the parent. We report a case of fatal
Jason L. Russell +2 more
openaire +4 more sources
Carbamazepine for schizophrenia [PDF]
, 2007 Many people with schizophrenia do not achieve a satisfactory treatment response with just antipsychotic drug treatment and various adjunct medications are used to promote additional response. The antiepileptic carbamazepine is one such drug.To evaluate the effects of carbamazepine and its derivatives for the treatment of schizophrenia and related ...
Leucht, Stefan +3 more
openaire +4 more sources
Occurrence, distribution, and risk assessment of selected pharmaceuticals in municipal biosolids from the four wastewater treatment plants in Gauteng Province, South Africa [PDF]
Scientific ReportsThe presence of pharmaceutical residues in municipal biosolids is an emerging environmental concern due to their potential accumulation in agricultural soils following land application.
Matome Peter Ngoetjana +3 more
doaj +2 more sources
Non-recurrence of carbamazepine induced vitiligo after rechallenge with carbamazepine.
Iranian Journal of Psychiatry, 2013 Objective: Vitiligo is a rare side effect of carbamazepine whose exact mechanism is unknown. The aim of this report is to describe a single case of vitiligo induced by carbamazepine .
Masoomeh Saeedloo, Seyed Vahid Shariat
doaj +1 more source
Journal of Interdisciplinary Medicine, 2017 An uncomplicated, sensitive liquid chromatography linked to mass spectrometry (LC/MS) for evaluation of carbamazepine and carbamazepine-10,11-epoxide (its metabolite) in human plasma, human saliva, rat plasma, and rabbit plasma was developed.
Andonie Dan +4 more
doaj +3 more sources
Method of simultaneous determination of carbamazepine and carbamazepine-10,11-epoxide by HPLC-MS/MS
Регуляторные исследования и экспертиза лекарственных средств, 2018 Carbamazepine is the drug of first choice in the treatment of trigeminal neuralgia, epilepsy and other neurological diseases. Carbamazepine is known to have a narrow therapeutic range, and hereby the auto-induction of its metabolism with prolonged use ...
T. A. Rodina +7 more
doaj +2 more sources
Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]
, 2000 In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Waldemar Greil +3 more
core +1 more source
Carbamazepine overdose after exposure to simethicone: a case report
Journal of Medical Case Reports, 2008 Introduction Carbamazepine is an anticonvulsant drug and is also used as a treatment for patients with manic-depressive illness, post-herpetic neuralgia or phantom limb pain. The drug itself has many drug interactions. Simethicone is an antifoaming agent
Guneysel Ozlem +3 more
doaj +1 more source
Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine) [PDF]
, 2007 Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica.
Yousef Javadzadeh +8 more
core +1 more source