Results 21 to 30 of about 83,313 (237)
Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8
Journal of Medicinal Chemistry, 2020 Misregulation of Wnt signaling is common in human cancer. The development of small molecule inhibitors against the Wnt receptor, frizzled (FZD), may have potential in cancer therapy.
Yuguang Zhao +4 more
semanticscholar +1 more source
Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
, 1983 Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W. +5 more
core +1 more source
Impact of variability in carbamazepine raw materials on drug release [PDF]
, 2011 Variability in raw materials presents a challenge for pharmaceutical companies. The varying physicochemical properties can critically influence drug release and bioavailability of the final dosage form.
Flicker, Felicia
core +1 more source
The ISME Journal, 2018 Antibiotic resistance is a severe global threat for public health, causing around 700,000 deaths per year. Horizontal gene transfer (HGT) is one of the most significant pathways to disseminate antibiotic resistance.
Yue Wang +6 more
semanticscholar +1 more source
Renal Replacement Therapy, 2020 Background Carbamazepine-induced acute kidney injury is mainly caused by acute tubulointerstitial nephritis. Only one case of carbamazepine-induced eosinophilic granulomatosis with polyangiitis (EGPA) with acute kidney injury has been reported.
Tetsuya Abe +13 more
doaj +1 more source
Clinical pharmacology and therapy, 2018 The variant allele HLA‐B*15:02 is strongly associated with greater risk of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine.
E. Phillips +13 more
semanticscholar +1 more source
Molecules, 2015 The majority of drugs have a low dissolution rate, which is a limiting step for their absorption. In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems (S-SMEDDS) and solid self-nanoemulsifying drug delivery ...
Marko Krstić +3 more
doaj +1 more source
Differential treatment of bipolar disorder with old and new antiepileptic drugs [PDF]
, 1998 Although lithium remains the preferred medication for bipolar disorders, new investigations suggest that only 60 to 80% of patients have a good response with a classical presentation.
Normann, C. +7 more
core +1 more source
Effects of Carbamazepine On Vascular Risk Factors and Atherosclerosis in Epileptic Children
, 2021 Objectives:The aim of our study was to investigate the presence of increased cardiovascular risk in epileptic children treated with carbamazepine. This study was designed to evaluate the relation of carbamazepine and atherosclerosis by investigating the ...
Asli Imran YILMAZ +3 more
core +1 more source
Carbamazepine Enhances Adipogenesis by Inhibiting Wnt/β-Catenin Expression
Cells, 2019 Carbamazepine is a drug that is widely used in the treatment of epilepsy and bipolar disorder. The prevalence of obesity in patients treated with carbamazepine has been frequently reported.
Dong Uk Im +3 more
doaj +1 more source