Results 71 to 80 of about 2,372,972 (378)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Absence Epilepsy and Paroxysmal Dyskinesia

Pediatric Neurology Briefs, 2002
Six patients aged 6 to 27 years (mean, 14 years) with childhood absence epilepsy and paroxysmal dyskinesia (PD), identified at five European centers participating in a study group, are reported from Great Ormond Street Hospital, London, UK.
J Gordon Millichap
doaj   +1 more source

Contributions of Magnetoencephalography to Understanding Mechanisms of Generalized Epilepsies: Blurring the Boundary Between Focal and Generalized Epilepsies?

Frontiers in Neurology, 2022
According to the latest operational 2017 ILAE classification of epileptic seizures, the generalized epileptic seizure is still conceptualized as “originating at some point within and rapidly engaging, bilaterally distributed networks.” In contrast, the ...
Thandar Aung, Jeffrey R. Tenney, Anto I. Bagić   +2 more
doaj   +1 more source

Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]

, 2010
High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman, Finnerty, Gerald T, Jefferys, John G R, Jiruska, Premysl, Lofti, Noosheen, Powell, Andrew D   +5 more
core   +3 more sources

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions

Epilepsia, 2022
The 2017 International League Against Epilepsy classification has defined a three‐tier system with epilepsy syndrome identification at the third level. Although a syndrome cannot be determined in all children with epilepsy, identification of a specific ...
N. Specchio, E. Wirrell, I. Scheffer, R. Nabbout, K. Riney, Pauline Samia, M. Guerreiro, Sam Gwer, S. Zuberi, J. Wilmshurst, Elissa G. Yozawitz, Ronit M. Pressler, E. Hirsch, S. Wiebe, H. Cross, E. Perucca, S. Moshé, P. Tinuper, S. Auvin   +18 more
semanticscholar   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]

, 2017
The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji, Bathen-Noethen, Andrea, Bhatti, Sofie, Boettcher, Irene C, Cortez, Miguel A, Dietschi, Elisabeth, Fischer, Andrea, Flegel, Thomas, Hytönen, Marjo K, Hülsmeyer, Velia, James, Fiona, Kluger, Gerhard, Kornberg, Marion, Koskinen, Lotta LE, Leeb, Tosso, Lohi, Hannes, Matiasek, Kaspar, Rentmeister, Kai, Sarviaho, Riika, Tipold, Andrea, Tästensen, Carina, Wielaender, Franziska   +21 more
core   +1 more source

Sustained efficacy of closed loop electrical stimulation for long-term treatment of absence epilepsy in rats

Scientific Reports, 2017
Closed-loop brain stimulation is a promising alternative to treat drug-resistant epilepsies. In contrast to optogenetic interventions, transcranial electrical stimulation (TES) does not require cellular modification of neurons to be effective, and it is ...
Gábor Kozák, A. Berényi
semanticscholar   +1 more source

ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions

Epilepsia, 2022
In 2017, the International League Against Epilepsy (ILAE) Classification of Epilepsies described the “genetic generalized epilepsies” (GGEs), which contained the “idiopathic generalized epilepsies” (IGEs).
E. Hirsch, J. French, I. Scheffer, A. Bogacz, T. Alsaadi, M. Sperling, F. Abdulla, S. Zuberi, E. Trinka, N. Specchio, E. Somerville, Pauline Samia, K. Riney, R. Nabbout, Satish Jain, J. Wilmshurst, S. Auvin, S. Wiebe, E. Perucca, S. Moshé, P. Tinuper, E. Wirrell   +21 more
semanticscholar   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source