Results 81 to 90 of about 2,037,182 (380)

Sustained efficacy of closed loop electrical stimulation for long-term treatment of absence epilepsy in rats

open access: yesScientific Reports, 2017
Closed-loop brain stimulation is a promising alternative to treat drug-resistant epilepsies. In contrast to optogenetic interventions, transcranial electrical stimulation (TES) does not require cellular modification of neurons to be effective, and it is ...
Gábor Kozák, A. Berényi
semanticscholar   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

An estimate of the prevalence of epilepsy in Sub-Saharan Africa:A systematic analysis [PDF]

open access: yes, 2012
Epilepsy is a leading serious neurological condition worldwide and has particularly significant physical, economic and social consequences in Sub–Saharan Africa.
Adeloye, Davies   +5 more
core   +2 more sources

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno   +13 more
wiley   +1 more source

Epilepsy – A Brief Overview [PDF]

open access: yes, 2005
Epilepsy is a neurological condition in which an individual experiences chronic abnormal bursts of electrical discharge in the brain. These seizures can cause a variety symptoms depending on the areas of the brain affected. Symptoms can vary from mild to
Koyama, Alain
core  

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?

open access: yesCurrent Neuropharmacology, 2017
Background: Spike-wave discharges, underlying absence seizures, are generated within a cortico-thalamo-cortical network that involves the somatosensory cortex, the reticular thalamic nucleus, and the ventrobasal thalamic nuclei.
R. Celli   +9 more
semanticscholar   +1 more source

Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute   +5 more
wiley   +1 more source

Neurocognitive Profile of Absence Epilepsy Syndrome

open access: yesPediatric Neurology Briefs, 2001
Cognitive and language function was determined in 16 children (mean age, 9.2 years; range 6-16) with absence epilepsy compared to 16 controls at the University of Catania, Italy.
J Gordon Millichap
doaj   +1 more source

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