Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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The Ancylus transgression in the area of Espoo - the first Salpausselkä, southern Finland [PDF]
The extent and age of the Ancylus transgression was studied by means of shore marks in the field, biostratigraphy from 39 bog and lake basins, and radiocarbon determinations in the area of the Salpausselka zone, west of Helsinki, southern Finland.
O. Ristaniemi, G. Glückert
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The geological structure, structural relations with the underlying complexes, mineral composition, age and origin of sedimentary-volcanogenic and intrusive formations of the Chamberlain valley area (northern part of the Wedel Jarlsberg Land, Svalbard ...
Aleksandr N. Sirotkin +1 more
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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Miocene Slănic Tuff, Eastern Carpathians, Romania, in the Context of Badenian Salinity Crisis
New geochronological investigations for the Slănic Formation, correlated with previous bio- and lithostratigaphical information, allow for a better succession of events for the Middle Miocene, including the absolute age of the Badenian salinity crisis in
Ana-Voica Bojar +5 more
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The biostratigraphy of sediments deposited in the Lake Kaali meteorite impact structure, Saaremaa island, Estonia [PDF]
The results of lithological, biostratigraphical and chronostratigraphical studies on the Lake Kaali meteorite impact structure, Estonia (lat 58°22' N, long 22°40' E) are discussed. Two pollen diagrams and 18 radiocarbon dates from different materials are
L. Saarse +3 more
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Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
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Tectono-metamorphic evolution and timing of the melting processes in the Svecofennian Tonalite-Trondhjemite Migmatite Belt: An example from Luopioinen, Tampere area, southern Finland [PDF]
The Svecofennian Orogen is in southern Finland characterized by two major migmatite belts. These are the so-called Granite Migmatite Belt, in which Kfs-rich leucosomes predominate, and the Tonalite-Trondhjemite Migmatite Belt, which is characterized by ...
H. Mouri, K. Korsman, H. Huhma
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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
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Age of the Tokkalehto metagabbro and its significance to the lithostratigraphy of the early Proterozoic Kuusamo supracrustal belt, northern Finland [PDF]
The c. 30-km2 Tokkalehto metagabbro and associated sills and dykes intrude a large part of the western part of the early Proterozoic Kuusamo supracrustal belt in northern Finland. These rocks have previously been mapped as a metavolcanic unit, Greenstone
P.M. Evins, K. Laajoki
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