Results 21 to 30 of about 3,055,660 (264)
Chiroptical Signature and Absolute Configuration of Tröger’s Base-Based Triangular Macrocycles [PDF]
ACS OmegaLuis Palomo +6 more
doaj +2 more sources
Absolute configuration of dolichol [PDF]
Biochemical Journal, 1980 A derivative of dolichol was formed and then chemically degraded to a small fragment containing the sole centre of asymmetry of the original molecule. Polarimetric comparison of this derivative with a standard prepared from (R)-citronellol showed dolichol to have an S-configuration at C-3. To determine the optical purity of dolichol a diastereoisomeric
W L, Adair, S, Robertson
openaire +2 more sources
Journal of Natural Products, 2020 The application of flexible biphenyls as chiroptical probes for the absolute configuration assignment to chiral natural products is described. The method is straightforward and reliable and can be applied to conformationally mobile and ECD silent ...
E. Santoro +6 more
semanticscholar +1 more source
Absolute Configuration of In Situ Crystallized (+)-γ-Decalactone
Chemistry, 2021 Knowledge about the absolute configuration of small bioactive organic molecules is essential in pharmaceutical research because enantiomers can exhibit considerably different effects on living organisms.
Michael Patzer +3 more
doaj +1 more source
Comparative study of the vibrational optical activity techniques in structure elucidation : the case of galantamine [PDF]
, 2019 The absolute configuration of the alkaloid galantamine was studied using a range of solution-state techniques; nuclear magnetic resonance (NMR), vibrational circular dichroism (VCD), and Raman optical activity (ROA). While the combined use of NMR and VCD
Bultinck, Patrick +4 more
core +2 more sources
Absolute Configuration of Falcarinol (9Z-heptadeca-1,9-diene-4,6- diyn-3-ol) from Pastinaca sativa [PDF]
, 2013 Falcarinol (9Z-heptadeca-1,9-diene-4,6-diyn-3-ol; 1) is a polyacetylene commonly found in several plant families. The absolute configuration of naturally occurring 1 is not clear and contradictory results have been reported in the literature ...
Brunton, Nigel +4 more
core +1 more source
Acta Crystallographica Section E, 2013 The absolute configuration of the title compound, C16H23BrCl2, has been deduced from the chemical pathway and fully confirmed by refinement of the Flack and Hooft parameters.
Abdoullah Bimoussa +4 more
doaj +1 more source
(1S)-1-phenylethanaminium 4-{[(1S,2S)-1-hydroxy-2,3-dihydro-1H,1'H-[2,2'-biinden]-2-yl]methyl}benzoate [PDF]
, 2012 Copyright 2012 © International Union of Crystallography.The title molecular salt, C8H12N+·C26H21O3-, contains a dimeric indane pharmacophore that demonstrates potent anti-inflammatory activity.
Frampton, CS +4 more
core +1 more source
Electron diffraction determines molecular absolute configuration in a pharmaceutical nanocrystal
Science, 2019 Dynamical refinement spots a difference For chiral molecules used in drugs, one isomer can have beneficial bioactivity, whereas the others are useless or even harmful.
P. Brázda, L. Palatinus, M. Babor
semanticscholar +1 more source