Results 41 to 50 of about 44,686 (267)
Speculative vs. Transcendental: a Deleuzian Response to Meillassoux [PDF]
La Deleuziana, 2020 In “Iteration, Reiteration, Repetition”, Quentin Meillassoux accuses Deleuze of forming a subjectalist philosophical system, that is to say, despite his critiques of subjectivism and representationalism, Deleuze absolutizes the correlation between ...
Mehdi Parsa
doaj
Absolute Continuity of Stable Seminorms
The Annals of Probability, 1986 The authors prove the following Theorem: Let \(\mu\) be a symmetric p- stable measure on a complete separable metric vector space E and let \(q: E\to R^+\) be a lower semicontinuous seminorm. Then the distribution function of q is absolutely continuous, except possibly at \(u_ 0=\inf \{u>0:\) \(F(u)>0\}\).
Byczkowski, T., Samotij, K.
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
DISCHARGE MANAGEMENT TO ENSURE CONTINUITY OF CARE: EXPERIENCE OF PORTUGUESE LIAISON NURSES
Cogitare Enfermagem, 2018 Objective: To describe the activities performed to ensure continuity of care by liaison nurses in hospital services. Method: Descriptive exploratory study with 107 nurses conducted from September 2016 to March 2017, in 15 hospitals in Portugal.
Maria Manuela Martins +5 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Absolute Convergence of Continued Fractions [PDF]
Proceedings of the American Mathematical Society, 1952 wheref1 is a number, {a,, a2, a3, } is a sequence of nonzero numbers, and { b1, b2, b3, * } is a sequence of numbers. We obtain conditions necessary and sufficient for (1.1) to converge absolutely, and we indicate their relationship to older sufficient conditions. We find a new characterization of positive definite continued fractions, whose importance
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source