Results 61 to 70 of about 1,190,251 (340)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Religious Feeling in Schleiermacher’s Standpoint and Otto’s Criticism on that

open access: yesComparative Theology, 2011
Friedrich Daniel Ernest Schleiermacher (1768-1834) was one of the most notable theologian and philosophers, who is known for his impressive attempts in modern theology after the age of enlightenment.
Shaghool, Y, Golzar Isfahani, M
doaj  

Charged-particle distributions in s=13 TeV pp interactions measured with the ATLAS detector at the LHC

open access: yesPhysics Letters B, 2016
Charged-particle distributions are measured in proton–proton collisions at a centre-of-mass energy of 13 TeV, using a data sample of nearly 9 million events, corresponding to an integrated luminosity of 170 μb−1, recorded by the ATLAS detector during a ...
G. Aad   +2869 more
doaj   +1 more source

Long-range potential fluctuations and 1/f noise in hydrogenated amorphous silicon

open access: yes, 2003
We present a microscopic theory of the low-frequency voltage noise (known as "1/f" noise) in micrometer-thick films of hydrogenated amorphous silicon. This theory traces the noise back to the long-range fluctuations of the Coulomb potential produced by ...
A. D. van Rheenen   +21 more
core   +1 more source

Temperature-dependent absolute refractive index measurements of synthetic fused silica [PDF]

open access: yesSPIE Proceedings, 2006
Using the Cryogenic, High-Accuracy Refraction Measuring System (CHARMS) at NASA's Goddard Space Flight Center, we have measured the absolute refractive index of five specimens taken from a very large boule of Corning 7980 fused silica from temperatures ranging from 30 to 310 K at wavelengths from 0.4 to 2.6 microns with an absolute uncertainty of +/-1 ...
Leviton, Douglas B., Frey, Bradley J.
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Religious Feeling in Schleiermacher’s Standpoint and Otto’s Criticism on that

open access: yesComparative Theology, 2010
  Friedrich Daniel Ernest Schleiermacher (1768-1834) was one of the most notable theologian and philosopher s, who is known for his impressive attempts in modern theology after the age of enlightenment.
Yosef Shaghool, Mozhgan Golzar Isfahani
doaj  

Multiphoton interaction phase shifts in attosecond science

open access: yesPhysical Review Research, 2021
Ab initio simulations of a range of interferometric experiments are used to identify a strong dependence on multiphoton phase shifts in above-threshold ionization (ATI).
Mattias Bertolino, Jan Marcus Dahlström
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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