Results 61 to 70 of about 206,257 (263)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

FRIEDRICH SCHLEIERMACHER'E GÖRE DİN

Felsefe Dünyası, 2013
Friedrich Schleiermacher'e göre, din temelde duygusal bir olgudur. Oldukça dar anlamıyla, o, mutlak bağımlılık duygusudur. Bu duygu Tanrı ile ilişki içinde bulunma bilinci ile bir ve aynıdır.
Cenan Kuvancı
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Neutrino oscillations in presence of diagonal elements of scalar NSI: an analytic approach

Journal of High Energy Physics
Scalar Non-Standard Interactions (SNSI) in neutrinos can arise when a scalar mediator couples to both neutrinos and standard model fermions. This beyond the Standard Model (BSM) scenario is particularly interesting as the SNSI contribution appears as a ...
Dharitree Bezboruah, Dibya S. Chattopadhyay, Abinash Medhi, Arnab Sarker, Moon Moon Devi   +4 more
doaj   +1 more source

Absolute and delay-dependent stability ofequations with a distributed delay

Discrete and Continuous Dynamical Systems, 2012
We study delay-independent stability in nonlinear models with a distributed delay which have a positive equilibrium. Models with a unique positive equilibrium frequently occur in population dynamics and other applications. In particular, we construct a relevant difference equation such that its stability implies stability of the equation with a ...
Braverman Elena, Zhukovskiy Sergey
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Disability and motorcycle taxi drivers in Cartagena, Colombia

Revista Facultad Nacional de Salud Pública, 2011
Objective: to estimate the functional dependency as a measure of disability in a group of motorcycle taxi drivers from Cartagena, Colombia. Methods: a retrospective descriptive study in which researchers reviewed 1123 files of motorcycle taxi drivers ...
Yaneth Herazo B, Regina Domínguez A, Sandra Olarte B, Liliseth Quitian C   +3 more
doaj  

Dependence of Multiband Absolute Magnitudes and Color Indexes of the Tip of the Red Giant Branch Stars on Metallicity in Galactic Globular Clusters

The Astrophysical Journal
The tip of the red giant branch (TRGB) stars have attracted intensive attention in recent years because their I -band absolute magnitudes, M _I , are often used for distance calibration in the Hubble constant measurements because of its almost ...
Zhenzhen Shao, Shu Wang, Biwei Jiang, Xiaofeng Wang, Zhishuai Ge, Haichang Zhu   +5 more
doaj   +1 more source