Results 101 to 110 of about 69,015 (252)

Predictive role of absolute lymphocyte count in daratumumab-treated patients with relapsed/refractory multiple myeloma. [PDF]

open access: yesKorean J Intern Med, 2023
Cho HJ   +17 more
europepmc   +2 more sources

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura   +9 more
wiley   +1 more source

Prognostic significance of absolute lymphocyte count and lymphocyte subsets in lymphomas.

open access: yesPrague medical report, 2010
Lymphocytopenia is a poor prognostic marker in initial staging of non- Hodgkin lymphomas (below 1.0 x 10(9)/l) and Hodgkin lymphoma (below 0.6 x 10(9)/l) and in relapsed diffuse large B cell lymphoma. Early lymphocyte recovery > or =0.5 x 10(9)/l after autologous and allogeneic stem cell transplantation is a significant predictor of tumor control and ...
openaire   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

open access: yesAdvanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz   +2 more
wiley   +1 more source

Patterns of Neutrophil to Lymphocyte Ratio Change in two Inflammatory Rheumatic Diseases: Systemic Lupus Erythematosus and Rheumatoid Arthritis

open access: yesActa Clinica Croatica
A high neutrophil to lymphocyte ratio (NLR) is a potential marker of systemic inflammation and predictor of worse outcomes in numerous diseases, but with no report on the pattern of change in NLR (changes in absolute neutrophil and lymphocyte counts ...
Antica Mihaliček   +4 more
doaj   +1 more source

Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment‐Resistant Subclones at the Time of Diagnosis

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Mantle cell lymphoma (MCL) is a B‐cell malignancy with a chronically relapsing clinical course and pronounced genetic heterogeneity. To investigate the clonal dynamics underlying early disease relapse, we performed single‐cell RNA sequencing of paired tumor samples collected at diagnosis and at first relapse. Inference of copy number variants (
Dmitry Manakov   +14 more
wiley   +1 more source

Epidemiology of Cancer‐Associated Venous Thromboembolism Across the United States

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Prior epidemiological studies on cancer‐associated venous thromboembolism (VTE) were limited by homogenous patient populations. We leverage Cosmos, a collaborative dataset of Epic electronic health record systems, to conduct an updated evaluation of cancer‐associated VTE in the United States (US).
Barbara D. Lam   +7 more
wiley   +1 more source

A The ratio of neutrophils l and the mean platelet volume to platelet count ratio as risk factors for febrile convulsions in Zakho

open access: yesZanco Journal of Medical Sciences
Background and objective: The most prevalent cause of convulsions in young children is febrile convulsions. The ratio of neutrophils to lymphocytes (NLR), the mean platelet volume (MPV), and the platelet count are indicators of inflammation.
Sherzad A. Mosa   +3 more
doaj   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito   +10 more
wiley   +1 more source

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