Results 91 to 100 of about 1,308,562 (279)

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

¬HUBUNGAN ABSOLUTE LYMPHOCYTE COUNT DENGAN BRIXIA SCORE PADA PASIEN COVID-19 Studi Observasional Analitik Pada Pasien Terkonfimasi COVID-19 di Rumah Sakit Islam Sultan Agung Semarang [PDF]

, 2023
Coronavirus disease (COVID-19) adalah penyakit yang disebabkan oleh virus SARS-CoV-2 dengan penyebaran sangat cepat melalui saluran pernafasan. Skrining awal penyakit COVID-19 sangat berguna untuk mencegah penularan lebih lanjut.
Arrumaisha, Arrumaisha
core   +1 more source

Blood Investigation and Cardiac Markers: The Key Role to Rule Out Hospital Outcome of Myocardial Infraction in Tertiary Cardiac Care Centre

Journal of Medical Sciences and Health
Background: In-hospital mortality varies substantially across hospitals after myocardial infarction. This study is intended for physicians, nurses, and allied healthcare personnel who care for patients with suspected or established acute ...
Payal Tripathi, Himani Pandya, Aparna Singh, Rupali Patil, Brijesh Patel   +4 more
doaj   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Predictive Value of Procalcitonin and Lymphocyte Count for Secondary Infection Risk in Patients Hospitalized with Influenza Pneumonia [PDF]

Introduction: The primary complications of influenza are secondary infections, particularly pneumonia, which contribute to increased morbidity and mortality.
Esra TEKİN, Can ILGIN, Sait KARAKURT, Seda SEVEN İNCİ   +3 more
core   +1 more source

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Other laboratory data of subjects according to age group (WBC, percent and absolute lymphocyte count, CRP, serum protein, serum albumin).

, 2016
Other laboratory data of subjects according to age group (WBC, percent and absolute lymphocyte count, CRP, serum protein, serum albumin).
Jong Sun Park (2816584), Won Bae (2816569), Ho Il Yoon (2816581), Choon-Taek Lee (2816575), Young-Jae Cho (2816587), Eun Young Song (2816578), Se Joong Kim (2816572), Yeon Joo Lee (541858), Jae Ho Lee (493452), Jae-Joon Yim (139591), Kyoung Un Park (835602)   +10 more
core   +1 more source