Results 101 to 110 of about 1,308,562 (279)

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Kinetics of CD4+ T-Lymphocyte in Dengue Virus Infection

Majalah Kedokteran Bandung, 2014
Cellular immunity plays an important role in viral infection. The activation of effector T-lymphocytes and the release of cytokines define the course of dengue viral infection. CD4⁺ T-lymphocyte induces the immunopathology via various mechanisms; however,
Ida Safitri Laksono, Umi S Intansari
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Clinical laboratory parameters in patients with COVID-19

Revista Cubana de Medicina Militar, 2021
Introduction: Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19. Objective: To describe the clinical laboratory parameters in patients diagnosed with COVID-19.
Naivy Sánchez Vera, Danay Saavedra Hernández, Carlos Jorge Hidalgo Mesa, Maykel Aguila López, Gladys Abreu Gutiérrez, Vivian Herrera González, Iliana Teresa Rodríguez García   +6 more
doaj  

Differentiating chronic lymphocytic leukemia from monoclonal B-lymphocytosis according to clinical outcome: on behalf of the GIMEMA chronic lymphoproliferative diseases working group

Haematologica, 2011
Background Optimal lymphocyte parameters and thresholds for the diagnosis of chronic lymphocytic leukemia have been proposed by The National Cancer Institute sponsored Working Group and recently updated by the International Workshop on chronic ...
Stefano Molica, Francesca R. Mauro, Diana Giannarelli, Francesco Lauria, Agostino Cortelezzi, Maura Brugiatelli, Vincenzo Liso, Antonio Cuneo, Robin Foà   +8 more
doaj   +1 more source

Prediction of CD4+ T lymphocyte count in HIV patients from their total leukocyte count and previous CD4+ counts

Introduction CD4+ T lymphocyte count is a high-cost para-clinical test, essential for follow-up of human immuno-deficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients.
César Alejandro Váldes Cadena, Signed Esperanza Bohorquez Prieto, Joao Cuesta   +2 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

The triple A model (age, absolute neutrophil count, absolute lymphocyte count‐AAA) predicts survival and thrombosis in polycythemia vera

American Journal of Hematology
To the Editor: BCR::ABL1-negative chronic myeloproliferative neoplasms (MPNs), polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis are characterized by constitutive activation of the JAK-STAT signaling pathway caused by mutations in the Janus Kinase 2 (JAK2), carelticulin, or thrombopoetin receptor genes.
Ivan Krecak, Danijela Lekovic, Isidora Arsenovic, Hrvoje Holik, Ivan Zekanovic, Martina Moric Peric, Marko Lucijanic   +6 more
openaire   +4 more sources

Counting Absolute Number of Lymphocytes in Quail Whole Blood by Flow Cytometry

Journal of Veterinary Medical Science, 2005
In a previous study, we reported a new method for counting quail blood cells. After quail blood cells were stained with fluorescent lipophilic dye (DiOC6(3)), absolute counts of erythrocytes, granulocytes, and monocytes were obtained by means of flow cytometry (FC).
UCHIYAMA, Rie, MORITOMO, Tadaaki, KAI, Osamu, UWATOKO, Kazuhiro, INOUE, Yuki, NAKANISHI, Teruyuki   +5 more
openaire   +3 more sources

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source