ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Background and objectives: In patients with coronavirus disease 2019 (COVID-19), white blood cell (WBC) abnormalities have been found worldwide with significant inter-regional differences.
Rajendra Zope +5 more
doaj
Tumor-associated and immunochemotherapy-dependent long-term alterations of the peripheral blood NK cell compartment in DLBCL patients [PDF]
Natural Killer (NK) cells are a key component of tumor immunosurveillance and thus play an important role in rituximab-dependent killing of lymphoma cells via an antibody-dependent cellular cytotoxicity (ADCC) mechanism.
Battella, Simone +13 more
core +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Survival prediction in mesothelioma using a scalable lasso regression model: instructions for use and initial performance using clinical predictors [PDF]
Introduction: Accurate prognostication is difficult in malignant pleural mesothelioma (MPM). We developed a set of robust computational models to quantify the prognostic value of routinely available clinical data, which form the basis of published MPM ...
Blyth, Kevin G. +5 more
core +1 more source
Measuring percent lymphocytes by flow cytometry to calculate absolute lymphocyte subset counts for HIV + specimens [PDF]
AbstractA comparison was made of lymphocyte percentages from an automated hematology analyzer (ELT 15) vs. a fluorescence flow cytometer (Cytofluorograf). The hematology values were consistently higher than the flow (by greater than 10% for 13 of 50 HIV + specimens). The findings were similar to three other pairings: H*1 vs.
H B, Gale, K, Henry
openaire +2 more sources
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Analisis Kuantitas dan Hitung Jenis Leukosit pada Petugas Radiologi di Balai Besar Kesehatan Paru Masyarakat (Bbkpm) Makassar [PDF]
The Radiology Officer is one of the groups that has a risk to the danger of radiation exposure and it caused of the healthy in the certain level. Then, it could cause the Chronis disease until with the death.
Armah, Z. (Zulfian) +2 more
core
Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes [PDF]
Abstract Background The immune system strongly influences outcome in patients with ovarian cancer. In particular, the absolute lymphocyte count in peripheral blood (ALC) and the presence of tumor-infiltrating lymphocytes (TIL) have each been associated with favourable prognosis.
Milne, Katy +9 more
openaire +4 more sources
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source

