Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count [PDF]
Clozapine is effective at reducing symptoms of treatment-resistant schizophrenia, but it can also induce several adverse outcomes including neutropenia and agranulocytosis. We used linear mixed-effect models and structural equation modelling to determine
Siobhan K. Lock +9 more
doaj +2 more sources
Absolute neutrophil count nadir in healthy pediatric patients with the Duffy-null phenotype [PDF]
Lauren E. Merz +5 more
openaire +3 more sources
Inflammatory Markers in Lung Cancer- A Comparative Cross-sectional Study [PDF]
Introduction: Lung cancer is the most common cause of cancer mortality worldwide, principally because of its late diagnosis. Chronic inflammation plays a significant role in tumour growth and progression via increasing the levels of inflammatory markers ...
Manisha Jain +5 more
doaj +1 more source
The Study of Correlation between Different Complete Blood Count Parameters in Acute Coronary Syndromes [PDF]
Introduction: Red Blood Cell (RBC) count, White Blood Cell (WBC) count, Platelets and their indices correlates with increased risk and severity of Acute Coronary Syndrome (ACS).
Abhey Chawla +4 more
doaj +1 more source
Hematological Manifestations of COVID-19 and its correlation with outcome – A retrospective study
Background and Aim: The objective was to study the hematological manifestations of disease caused by novel coronavirus 2019 (COVID-19) and evaluate the association between absolute neutrophil count (ANC), absolute lymphocyte count (ALC), neutrophil ...
Bobby Abraham +2 more
doaj +1 more source
Prognostic Significance of the Ratio of Absolute Neutrophil Count to Absolute Lymphocyte Count in Classic Hodgkin Lymphoma [PDF]
Abstract The aim of this study was to determine the prognostic effect of the absolute neutrophil count/absolute lymphocyte count ratio (ANC/ALC ratio) in patients with classic Hodgkin lymphoma (cHL). We performed a retrospective analysis of 312 patients with cHL.
Young Wha, Koh +8 more
openaire +2 more sources
Reduction in Absolute Neutrophil Counts in Patient on Clozapine Infected with COVID-19 [PDF]
Despite its severe adverse effects, such as agranulocytosis, clozapine is the primary treatment for treatment-resistant schizophrenia. The established clozapine monitoring system has contributed to reducing agranulocytosis incidence and mortality rates.
Fitri Fareez Ramli +4 more
openaire +2 more sources
Clinico-haematological profile in COVID-19 patients: an observational study at tertiary care center
Background: It is known as in other viral infections, severe acute respiratory syndrome coronavirus 2 infections, can be associated with haematological changes and often has the potential to optimize the monitoring of the infectious process and their ...
Jayalaxmi Yadav Kallur +3 more
doaj +1 more source
The Diagnostic Value of Absolute Neutrophil Count, Band Count and Morphologic Changes of Neutrophils in Predicting Bacterial Infections [PDF]
<i>Objectives:</i> To evaluate the value of neutrophil left shift parameters and neutrophil morphologic changes in diagnosing acute bacterial infections. <i>Materials and Methods:</i> Peripheral blood samples were obtained from 105 patients who had a positive culture for bacteria.
Layla A, Al-Gwaiz, Hanan H, Babay
openaire +2 more sources
Background and Objectives: Diagnostic markers to detect diabetic nephropathy at the early stage are important as early intervention can slow the loss of kidney function. Currently, there are very few diagnostic markers available.
G N Devamsh +4 more
doaj +1 more source

