Results 231 to 240 of about 1,274,743 (284)

Predictive modeling of clonal hematopoiesis across diverse cohorts. [PDF]

Blood Adv
Batchi-Bouyou AL, Tran D, Raddatz M, Gao T, Vlasschaert C, Sharber B, Liu J, Petrone G, Chan ICC, Beeler JS, Mustion G, Bick AG, Devlin SM, Bolton KL.   +13 more
europepmc   +1 more source

Dynamic neutrophil-to-lymphocyte ratio as an independent prognostic marker of overall survival in patients receiving immune checkpoint inhibitors: a Latin American cohort study. [PDF]

Front Oncol
Chatterjee P, Insagaray B, Ferraz T, González M, Muñoz G, Pombo V, Barrios R, Cuello M.   +7 more
europepmc   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Diagnostic utility of neutrophil CD64 for early detection of neonatal sepsis in southwestern Nigeria: a comparative case-control study. [PDF]

BMC Pediatr
Ajetunmobi IA, Ogbenna AA, Sayomi BA, Olaniyan OA, Olowookere KA, Muhibi MA.   +5 more
europepmc   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Predicting early acute pancreatitis severity using WBC, neutrophil count, NLR, and glucose levels. [PDF]

Medicine (Baltimore)
Li Z, Lou Y, Zhang G, Fang X, Chen S.
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Systemic inflammation and prognosis in patients with RAS/BRAF wild-type metastatic colorectal cancer receiving anti-EGFR therapy: A real-world cohort study. [PDF]

Colorectal Dis
Appleyard JW, Elliott F, Sapanara NL, Zhang L, Kurkure U, Seligmann JF, West NP, Shanmugam K, Quirke P, Williams CJM, N6 Collaboration.   +10 more
europepmc   +1 more source

Striatal Dopaminergic Reserve Shapes the Longitudinal Impact of Peripheral Immune Activation on Motor Progression in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. Objectives To examine whether baseline and time‐varying neutrophil‐to‐lymphocyte ratio (NLR) relate to motor ...
Osman Kahveci, Ulaş Ay, Tamer Demiralp
wiley   +1 more source

Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple‐negative breast cancer

The Journal of Pathology, EarlyView.
Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification, a significant cancer alteration with both prognostic and therapeutic relevance, lacks a standardized definition. The relationship between FGFR1 copy number (CN) variations and tumour microenvironment (TME) characteristics also remains poorly understood.
Yike Gao, Fei Yao, Junyi Pang, Tianlin Sun, Changbin Zhu, Shafei Wu, Zhiyong Liang   +6 more
wiley   +1 more source