Results 81 to 90 of about 1,274,743 (284)
Absolute neutrophil count at different time points after vaccination on day 0.
, 2016 (A & B) adjuvanted seasonal TIV. (C) seasonal TIV. (D) attenuated live yellow fever vaccine. (A, C & D) conducted as inpatients. (B) conducted as outpatients.Odile Launay (78130), Caroline L. Bodinham (315948), Allan Saul (34133), Audino Podda (90166), Annelies Aerssens (3143493), Alessandra Anemona (202929), Pierre Loulergue (3143487), Vincent Muturi-Kioi (3143490), David Lewis (245511), Geert Leroux-Roels (199739), Nicola Groth (3143496) +10 morecore +1 more sourceCoixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu +20 morewiley +1 more sourceCopper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis
Advanced Science, EarlyView.This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang +7 morewiley +1 more sourceMultiple Loci Are Associated with White Blood Cell Phenotypes [PDF]
, 2011 White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it varies widely among healthy individuals. Total WBC count and its constituent subtypes have been shown to be moderately heritable, with the heritability ...Taylor, K, Döring, Angela, Meisinger, C. (Christa), Kushang V Patel, Fox, Caroline S., Garner Stephen F., Wichmann HE, Uitterlinden AG, Taylor Kent, Witteman, JC, Wiggins Kerri L., Reiner, AP, Lin JingPing, Andrew B. Singleton, Neil A Zakai, Biffi Alessandro, Folsom, AR, Matsuda K, Völzke Henry, Kamatani Y, H.-Erich Wichmann, Pirastu Nicola, Bandinelli, S, Longo Dan L., Eiriksdottir, Gudny, Patel, K.V. (Kushang), Glazer, NL, Toshiko Tanaka, Kamatani N, Illig Thomas, Nakamura, Y. (Yusuke), Nicole L Glazer, Uitterlinden, Andre G., Toniolo, D. (Daniela), Couper, DJ, Smith, AV, Levy D, Mangino Massimo, van Rooij Frank J. A., Tsunoda T, Thein SL, Naoyuki Kamatani, Liu, Y, Ben A. Oostra, Fox Caroline S., Fox CS, Cupples L. Adrienne, Wilson, J.G. (James), Tönjes, Anke, Biffi, A. (Alessandro), Van Duijn, CM, Boerwinkle, Eric, Nalls, Michael A., Wiggins, Kerri L., Eiriksdottir, G, Smith AV, Janine F Felix, Toshihiro Tanaka, O'Donnell, CJ, Frayling, Timothy M., Wichmann, H.E. (Heinz Erich), Gasparini, P, Moore, M. (Matt), Stefania B, Boerwinkle, E, Uitterlinden, AG, Wood, Andrew R., Illig, T. (Thomas), Lettre, Guillaume, Bis, JC, Tamara B Harris, Folsom, A.R. (Aaron), Harris, T.B. (Tamara), Gieger, C, Voelker, Uwe, Levy Daniel, Meisinger, Christa, Levy, Daniel, Wiggins, K.L. (Kerri), Chen MH, Tamara B. Harris, Toniolo, D, Ouwehand, W.H. (Willem), Kazuhiko Yamamoto, Cupples, L.A. (Adrienne), Melzer, D, Lagou, Vasiliki, Couper, David J., Cornelia M van Duijn, Matsuda Koichi, Kushang V. Patel, Felix, JF, Yamamoto, K, Wilson JG, Stephen F. Garner, Kerri L, Er Teumer, Prokopenko I, Matt Moore, van Rooij, Frank J. A., Taylor, Kent, Ferrucci, L. (Luigi), Chong, S. (Sean), Sambrook J, Gieger C, Gieger Christian, Folsom Aaron R., Chong, Sean, Wood, AR, Garcia M, Garcia, M. (Melissa), Sambrook, J.G. (Jennifer), Hofman Albert, Couper, D. (David), Dan L, Sambrook, Jennifer, Nakamura Y, Wiggins, KL, Guillaume Lettre, Tatsuhiko Tsunoda, Nauck, Matthias, Abbas Dehghan, Aaron R. Folsom, Smith, A.V. (Albert Vernon), Stumvoll Michael, Lumley T, Daniela Toniolo, Völker, U. (Uwe), Willem H. Ouwehand, Rendon, A, Santhi K Ganesh, Arepalli, S, Lettre G, Illig T, Levy, D. (Daniel), Liu Y, Soranzo, N. (Nicole), Greinacher, A, Melzer, David, Thomas Illig, Völzke, H. (Henry), Nauck M, Aravinda Chakravarti, Neil A. Zakai, Andreas Greinacher, Bandinelli, Stefania, Prokopenko, Inga, O'Donnell CJ, Lettre, G, Christopher J O'Donnell, Okada, Y, Moore, Matt, Coresh Josef, Jacqueline C M Witteman, Couper David J., Nalls, M.A. (Michael), Gieger, C. (Christian), Frayling Timothy M., Garner SF, Gudnason, V. (Vilmundur), James G. Wilson, Kuhnel B, Sampath Arepalli, Mangino, M, Yamamoto, Kazuhiko, Chen, Ming-Huei, Chen, MH, Timothy M, Yang, Qiong, Yang, Q, Zakai, Neil A., Moore, M, Frayling TM, Singleton, Andrew B., Menzel, S, Koichi Matsuda, Fox, CS, Dehghan A, Tim D Spector, Takahashi A, Yang Qiong, Ferrucci, L, Garcia Melissa, Lettre Guillaume, Patel, KV, Toenjes, Anke, Thein Swee Lay, Jonathan Stephens, Willem H Ouwehand, Harris TB, Uitterlinden, A.G. (André), Felix, Janine F., Nalls MA, Alessandro Biffi, Greinacher, Andreas, Luigi Ferrucci, O'Donnell, C.J. (Christopher), Kubo Michiaki, Tönjes, A. (Anke), Aaron R Folsom, Völzke, H, Dehghan, Abbas, H-Erich Wichmann, Hofman A, Melissa Garcia, Gudnason, V, Gouskova Natalia A., Qiong Yang, Ferrucci Luigi, Reiner AP, Arepalli, Sampath, Vasiliki Lagou, Caroline S Fox, Frayling, T.M. (Timothy), Ganesh, Santhi K., Albert V Smith, Patel, Kushang V., Tsunoda, T. (Tatsuhiko), Coresh J, Cupples, LA, Lettre, G. (Guillaume), Garner, Stephen F., Bruce M Psaty, Smith, Albert V., Reiner, Alex P., Frayling, TM, Teumer, A, Stumvoll, M. (Michael), Daniel Levy, Matthias Nauck, Takahashi, A, Frank J. A. Van Rooij, Felix, J.F. (Janine), Prokisch H, Arepalli S, Hernandez, Dena G., van Duijn, Cornelia M., Atsushi Takahashi, Zakai, N.A. (Neil), Janine F. Felix, Psaty, B.M. (Bruce), Patel Kushang V., Harris, TB, Yusuke Nakamura, Cornelia M. Van Duijn, Yoichiro Kamatani, Zakai NA, Prokopenko Inga, Gouskova, N.A. (Natalia), Witteman Jacqueline C. M., Patel KV, Felix Janine F., Wichmann H.-Erich, Tikka-Kleemola, P. (Päivi), Oostra, B.A. (Ben), Tsunoda Tatsuhiko, Joshua C Bis, Stumvoll, Michael, Tim D. Spector, Lumley, Thomas, Andre ́ G. Uitterlinden, Oostra, BA, Wilson, James G., Kuhnel, B, Hofman, Albert, Zakai Neil A., Yongmei Liu, Rendon, Augusto, Eric Boerwinkle, Teumer Alexander, Yukinori Okada, André G. Uitterlinden, Glazer, Nicole L., Illig, Thomas, Dan L. Longo, Döring, A. (Angela), Biffi A, Voelzke, Henry, Völker Uwe, van Duijn Cornelia M., Oostra Ben A., Singleton AB, Wood Andrew R., Lumley Thomas, Ouwehand Willem H., Glazer Nicole L., Soranzo Nicole, Eiriksdottir Gudny, Stefania Bandinelli, Ganesh Santhi K., van Rooij FJ, Pirastu, N, Spector, TD, David J Couper, Pistis, G, Kamatani, Y. (Yoichiro), Tanaka, T, Cupples LA, Psaty BM, Dena G. Hernandez, Wichmann, H. -Erich, Arepalli Sampath, Psaty, Bruce M., Sean Chong, Kubo, M, Taylor K, Van Rooij, FJ, Wiggins KL, David Melzer, Timothy M. Frayling, Henry Völzke, Bruce M. Psaty, O'Donnell Christopher J., Menzel, Stephan; id_orcid, L. Adrienne Cupples, Chong Sean, Thein, S.L., Lin, J., Jennifer Sambrook, Santhi K. Ganesh, Kuhnel Brigitte, Yang, Q. (Qiong Fang), Gouskova, NA, Tönjes, A, Kamatani Naoyuki, Kamatani, Naoyuki, Rendon, A. (Augusto), Witteman, Jacqueline C. M., Felix JF, Wilson James G., Okada, Yukinori, Longo DL, Tanaka Toshiko, Lin J, Bis, J.C. (Joshua), Ro Biffi, Takahashi, A. (Atsushi), Longo, Dan L., JingPing Lin, Teumer, A. (Alexander), Dehghan Abbas, Folsom, Aaron R., Prokopenko, I. (Inga), Völker U, Eiriksdottir G, Liu, Y. (YongMei), Moore Matt, Ferrucci, Luigi, Soranzo, N, Longo, D.L. (Dan), Dehghan, A, Jacqueline C. M. Witteman, Caroline S. Fox, Spector, Tim D., Michael Stumvoll, Lumley, T, Wood, A.R. (Andrew), Bis JC, Witteman JC, Arepalli, S. (Sampath), Sambrook, J, Döring Angela, Biffi, A, Sambrook Jennifer, Albert V. Smith, Frank J A van Rooij, Inga Prokopenko, Menzel, Stephan, Folsom AR, Hernandez, D.G. (Dena), Stumvoll, M, Hernandez DG, Anke Tönjes, Bis Joshua C., Dena G. Hern, Kerri L. Wiggins, Timothy M Frayling, Pistis, G. (Giorgio), Tanaka Toshihiro, Vilmundur Gudnason, Meisinger, C, Doering, Angela, Nicola Pirastu, Tsunoda, Tatsuhiko, Völker, Uwe, Singleton Andrew B., O'Donnell, Christopher J., Eiriksdottir, G. (Gudny), Thein, Swee Lay, Meisinger C, Zakai, NA, van Duijn CM, Kamatani Yoichiro, Lagou V, Menzel S, Natalia A Gouskova, Coresh, J. (Josef), Kent Taylor, Prokisch, Holger, Menzel, S. (Stephan), Rendon Augusto, Mangino, Massimo, Christopher J. O’donnell, Völzke, Henry, Kamatani, N, Wichmann, HE, Coresh, Josef, Völker, U, Lin, JingPing, Kamatani, Y, Hernandez, DG, Stephens, J. (Jonathan), Alex P. Reiner, Nakamura Yusuke, Mangino M, Stephens, Jonathan, Levy, D, Boerwinkle, E.A. (Eric), Okada Yukinori, Kerri L Wiggins, Stephan Menzel, Bis, Joshua C., Tanaka, T. (Toshiko), Alex P Reiner, Tsunoda, T, Massimo Mangino, Chakravarti Aravinda, Lin, J, Thomas Lumley, Teumer, Alexander, Chakravarti, A. (Aravinda), Brigitte Kuhnel, Fox, C.S. (Caroline), Ouwehand, WH, Harris, Tamara B., Moore M, Michael A. Nalls, Stephens Jonathan, Nicole L. Glazer, Gouskova NA, Pistis, Giorgio, Illig, T, David J. Couper, Bandinelli, S. (Stefania), Stephen F Garner, Spector Tim D., Ming-Huei Chen, Toniolo, Daniela, Cupples, L. Adrienne, Gudnason V, Toniolo Daniela, Nauck Matthias, Nauck, M, Gudnason, Vilmundur, Thein, SL, Kuhnel, Brigitte, Prokopenko, I, Giorgio Pistis, Kubo, Michiaki, Melzer D, Nakamura, Yusuke, Prokisch Holger, Smith Albert V., Yamamoto Kazuhiko, Longo, DL, Ben A Oostra, Garner, SF, Liu, Yongmei, Garcia, Melissa, Christopher J. O'Donnell, Menzel Stephan, Völzke H, Gasparini, Paolo, Reiner, A.P. (Alex), Singleton, A. (Andrew), Gudnason Vilmundur, Greinacher A, Spector, T.D. (Timothy), Matsuda, Koichi, Nakamura, Y, Chen Ming-Huei, Dehghan, A. (Abbas), Stephens, J, Soranzo, Nicole, Chakravarti, A, Andrew R Wood, Boerwinkle Eric, Chong S, Hofman, A. (Albert), Dena G Hernandez, Melzer David, Biffi, Alessandro, Albert Hofman, Matsuda, K. (Koichi), Kuhnel, B. (Brigitte), Nalls, MA, Harris Tamara B., Andrew R. Wood, Prokisch, H. (Holger), Tönjes Anke, Uitterlinden André G., Pirastu, N. (Nicola), André G Uitterlinden, Melzer, D. (David), Rooij, F.J.A. (Frank) van, Meisinger Christa, Tanaka T, Greinacher, A. (Andreas), Ouwehand WH, Natalia A. Gouskova, Ganesh, S.K. (Santhi), Gieger, Christian, Kubo M, Josef Coresh, Rendon A, Ganesh SK, Nicole Soranzo, Coresh, J, Mangino, M. (Massimo), Michael A Nalls, Glazer, N.L. (Nicole), Döring A, Teumer A, Liu Yongmei, Tanaka, Toshihiro, Nalls Michael A., Chakravarti, Aravinda, Wichmann, Heinz-Erich, Toniolo D, Alexander Teumer, Nauck, M. (Matthias), Stephens J, Kubo, M. (Michiaki), Oostra, Ben A., Boerwinkle E, Christian Gieger, Kamatani, Yoichiro, Stumvoll M, Psaty, BM, Takahashi, Atsushi, Bandinelli Stefania, Wood AR, Pistis G, Spector TD, Ferrucci L, Matsuda, K, Augusto Rendon, Hernandez Dena G., Lagou Vasiliki, Oostra BA, Lagou, V, Tanaka, Toshiko, Yamamoto K, Chong, S, Willem H, Paolo Gasparini, Dan L Longo, Yamamoto, K. (Kazuhiko), Tönjes A, Andrew B Singleton, Taylor, K.D. (Kent), O'Donnell, Christopher J., Swee Lay Thein, Couper DJ, Joshua C. Bis, Hofman, A, Wilson, JG, Gasparini Paolo, Reiner Alex P., Lumley, T. (Thomas), Yang Q, Angela Döring, Singleton, AB, Gasparini, P. (Paolo), Okada, Y. (Yukinori), Garcia, M, Psaty Bruce M., Takahashi Atsushi, Bandinelli S, Döring, A, Christa Meisinger, Lagou, V. (Vasiliki), Witteman, J.C.M. (Jacqueline), Pistis Giorgio, Pirastu, Nicola, James G Wilson, Greinacher Andreas, Soranzo N, Chen, M-H. (Ming-Huei), Chakravarti A, Prokisch, H, Uwe Völker, H. -erich Wichmann, Garner, S.F. (Stephen), Gudny Eiriksdottir, Okada Y, Aaron R, L Adrienne Cupples, Gouskova, Natalia A., Glazer NL, Ganesh, SK, Ouwehand, Willem H., Holger Prokisch, Michiaki Kubo, Chen, Ming Huei, Uitterlinden, André G.; id_orcid, van Rooij, Frank J.A.; id_orcid +606 morecore +1 more sourceIntegrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution
Advanced Science, EarlyView.This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu +12 morewiley +1 more source