Results 91 to 100 of about 780 (198)
We examined the influence of denoising approaches on diagnostic differences in network topology across the Alzheimer's disease continuum. We show that the directionality of the diagnostic differences in network topology, particularly in global metrics of network segregation, can vary based upon the denoising approach employed.
Jenna K. Blujus +2 more
wiley +1 more source
Proteomic Biomarker Discovery in Breast Cancer: Advances, Challenges, and Translational Prospects
ABSTRACT Breast cancer remains a leading cause of cancer‐related morbidity and mortality among women worldwide. Despite major progress in genomic classification, molecular pathology, and targeted therapy, the identification of clinically reliable proteomics‐derived biomarkers for early detection, prognostic stratification, treatment response prediction,
Mahan Hassani +8 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
The Viscoelastic Behaviour of Auxetic Metamaterials
Stretch‐only auxetic unit‐cell viscoelastic models are extended from elastic honeycomb and keyway lattices using Maxwell and standard‐linear‐solid representations. Different horizontal and oblique relaxation responses make Poisson's ratio time‐ and frequency‐dependent, enabling tuneable auxetic behaviour for damping and adaptive structures.
Simon Preston +2 more
wiley +1 more source
ABSTRACT Aim We evaluate the phylogenetic relationships and taxonomic validity of Atlantic species of Labrisomus, identifying the lineages currently assigned to L. nuchipinnis, and assessing the role of biogeographic barriers in shaping the evolutionary history and geographic distribution of the genus. Location Atlantic Ocean.
Gabriel Soares Araujo +8 more
wiley +1 more source
Neural‐Initialized Newton: Accelerating Nonlinear Finite Elements via Operator Learning
ABSTRACT We propose a Newton‐based scheme, initialized by neural operator predictions, to accelerate the parametric solution of nonlinear problems in computational solid mechanics. First, a physics‐informed neural operator based on conditional neural fields or Fourier neural operators is trained to approximate the nonlinear parametric solution of the ...
Kianoosh Taghikhani +5 more
wiley +1 more source
This study investigates the nonlinear structural behavior of axially functionally graded material beams composed of steel and aluminum through a systematic computational approach.
Shaukat Abdur Rahman +4 more
doaj +1 more source
Critical Flow Velocity Analysis of Multi-Span Viscoelastic Micro-Bending Irrigation Pipelines
Irrigation pipelines are critical agricultural hydraulic facilities that often develop minor bending defects due to ground settlement or improper installation.
Sihao Wu +4 more
doaj +1 more source
ABSTRACTLattice systems are indispensable for modeling and analyzing physical phenomena in materials with discrete or heterogeneous micro‐ or meso‐structures. However, the computational requirements for practical engineering applications of lattice systems remain high.
Benjamin Werner +2 more
wiley +1 more source
ABSTRACT Numerical anisotropy and dispersion are inherent consequences of spatial discretization in finite element modeling of wave propagation. In two‐dimensional problems, these effects manifest not only as direction‐dependent phase and group velocities but also as angularly dependent numerical band gaps that may entirely suppress wave propagation ...
Wiktor Waszkowiak +3 more
wiley +1 more source

