Results 91 to 100 of about 11,192,626 (307)

Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose [PDF]

open access: gold, 2020
Danny Laurent   +9 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

ABSOLUTE MONARCHY IN WESTERN EUROPE AS A SOCIO-POLITICAL SYSTEM

open access: yesВестник Кемеровского государственного университета, 2015
The paper analyzes the European absolute monarchy as a socio-political phenomenon. The trends in the development of European countries and the main directions of transformation of political structures are discussed, defining features of absolute monarchy
O. N. Terekhova
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

About Defining the Referent Thermal Scale Points

open access: yesInterdisciplinary Description of Complex Systems, 2013
The absolute temperature T has a recognized physical meaning in equilibrium thermodynamics. The scale realized by the closely related Lagrange coefficient "b" usually figures as an auxiliary scale.
Josip Stepanić
doaj  

State savings: formation, structure and improvement of use

open access: yesУченые записки Российской академии предпринимательства, 2021
Process of formation of the state savings is shown in the article and the factors influencing it reveal. Dynamics of absolute and relative measures of the state savings is investigated.
A. N. Dmitriev
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

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