Results 51 to 60 of about 969,051 (320)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Network Synchronization in a Noisy Environment with Time Delays: Fundamental Limits and Trade-Offs

open access: yes, 2010
We study the effects of nonzero time delays in stochastic synchronization problems with linear couplings in an arbitrary network. Using the known exact threshold value from the theory of differential equations with delays, we provide the ...
Hunt, D., Korniss, G., Szymanski, B. K.
core   +1 more source

High-order numerical method for the nonlinear Helmholtz equation with material discontinuities in one space dimension [PDF]

open access: yes, 2007
The nonlinear Helmholtz equation (NLH) models the propagation of electromagnetic waves in Kerr media, and describes a range of important phenomena in nonlinear optics and in other areas.
Aubry   +32 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Surface gravity of neutron stars and strange stars

open access: yes, 2004
The upper bound on the value of the surface gravity, g_s, for neutron stars with equations of state respecting v_sound
Akmal   +28 more
core   +2 more sources

Differential transformation method for solving sixth-order boundary value problems of ordinary differential equations [PDF]

open access: yes, 2016
In this study, sixth-order boundary value problems for linear and nonlinear differential equations have been solved by using Differential Transformation Method (DTM). The numerical solutions are given in several examples.
Che Hussin, Che Haziqah   +4 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Equivalent differential equations for nonlinear dynamical systems [PDF]

open access: yes, 1970
A technique for obtaining approximate periodic solutions to nonlinear ordinary differential equations is investigated. The approach is based on defining an equivalent differential equation whose exact periodic solution is known. Emphasis is placed on the
Patula, Edward John
core   +2 more sources

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