Results 71 to 80 of about 9,755 (281)
Исследования и практика в медицине, 2018 The review of the literature examines the results of modern randomized cohort studies on the efficacy of alloplas-ty in hernia of the esophageal aperture of the diaphragm.
I. I. Rozenfel'd, D. L. Chilikina
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Implantable Shock Absorber for Medial Compartment Osteoarthritis
Video Journal of Sports MedicineBackground: Treating younger patients with isolated medial compartment osteoarthritis (OA) remains challenging, as these patients have often failed nonoperative treatment and wish to remain active, while surgeons are cautious using unicompartmental knee arthroplasty in young patients.
Jelle P. van der List, David C. Flanigan
openaire +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Safety of Silastic Sheet for Orbital Wall Reconstruction
Archives of Plastic Surgery, 2014 Background Many implants are being used for the reconstruction of orbital wall fractures. The effect of the choice of implant for the reconstruction of an orbital wall fracture on the surgical outcome is under debate.
Seong June Moon +3 more
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Implantable Shock Absorber: Breakthrough or Hype?
Current Reviews in Musculoskeletal MedicineAbstract Purpose of Review The goal of this review is to discuss the current understanding of implantable shock absorbers (ISA) including mechanism of action, usage in patients, patient outcomes and the future of this technology.
Jared A. Nowell, David C. Flanigan
openaire +2 more sources