Results 41 to 50 of about 8,258 (219)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Perfect Metamaterial Absorber [PDF]

Physical Review Letters, 2008
We present the design for an absorbing metamaterial element with near unity absorbance. Our structure consists of two metamaterial resonators that couple separately to electric and magnetic fields so as to absorb all incident radiation within a single unit cell layer. We fabricate, characterize, and analyze a metamaterial absorber with a slightly lower
Landy, N. I., Sajuyigbe, S., Mock, J. J., Smith, D. R., Padilla, W. J.   +4 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Numerical and Experimental Modelling of a Wave Energy Converter Pitching in Close Proximity to a Fixed Structure

Journal of Marine Science and Engineering, 2019
Free-floating bodies are commonly modelled using Cummins’ equation based on linear potential flow theory and including non-linear forces when necessary.
Pilar Heras, Sarah Thomas, Morten Kramer, Jens Peter Kofoed   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design of novel broadband absorber based on resistive film

Zhongguo Jianchuan Yanjiu, 2021
Objectives In order to improve the performance of traditional absorbing materials, a high-absorptivity broadband absorber is designed. Methods The absorber consists of a resistive film, dielectric substrate and metal ground plate. The element unit of the
Xujing HUANG, Guobin WAN
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A Polarization-Insensitive Broadband Terahertz Absorber Using Patterned Graphene

Nanomaterials, 2022
A polarization-insensitive broadband terahertz absorber with a sandwich structure of metal–dielectric-graphene is designed and simulated. The graphene is patterned as an array of graphene square blocks with circular apertures.
Maixia Fu, Jinyi Wang, Shaoshuai Guo, Zhaoying Wang, Pengxu Yang, Yingying Niu   +5 more
doaj   +1 more source