Results 51 to 60 of about 85,471 (316)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Active vibration isolation using an electrical damper or an electrical dynamic absorber

open access: yes, 2008
This paper describes a theoretical and experimental study to show how an electrical damper or an electrical dynamic absorber, implemented using an electromagnetic actuator and an accelerometer, can control vibration transmission through a vibration ...
Pietrzko, S.   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Electrodynamic absorber theory [PDF]

open access: yes, 2010
This work deals with questions that arise in classical and quantum electrodynamics when describing the phenomena of radiation reaction and pair creation. The two guiding ideas are the absorber idea of Wheeler and Feynman (i.e.
Deckert, Dirk-André
core  

Economic Shocks and Exchange Rate as a Shock Absorber in Indonesia and Thailand [PDF]

open access: yes
This study investigates the requirement for the exchange rate to be a shock absorber in Indonesia and Thailand from 1986 to 2007. In general, we find that the economic shocks have predominantly been asymmetric relative to the US and the Japanese ...
Siregar, Reza Y. Siregar, Goo, Siwei
core   +1 more source

Numerical and Experimental Modelling of a Wave Energy Converter Pitching in Close Proximity to a Fixed Structure

open access: yesJournal of Marine Science and Engineering, 2019
Free-floating bodies are commonly modelled using Cummins’ equation based on linear potential flow theory and including non-linear forces when necessary.
Pilar Heras   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Absorber Theory in Quantum Optics

open access: yes, 1986
The absorber theory of radiation is discussed with particular reference to its application to quantum optical phenomena. The essential feature of the theory is that the absorber is the source of the radiative reaction force. This is an advanced action of
Pegg, DT
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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