Results 51 to 60 of about 13,731 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Stable adaptive training for physics-informed neural networks in acoustic wave propagation [PDF]
JASA Express LettersPhysics-informed neural networks (PINNs) have emerged as a promising tool for simulating various phenomena. However, their application in underwater acoustics remains challenging, primarily due to the need to sample large computational domains and to ...
Márcio Marques +12 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
International Journal of Antennas and Propagation, 2014 The exact absorbing conditions (EAC) have been constructed and used for truncating an unbounded domain of computation in open initial boundary value problems, which describe space-time transformations of electromagnetic waves in axially symmetrical ...
Seil S. Sautbekov +3 more
doaj +1 more source
Time-Fractional Phase Field Model of Electrochemical Impedance
Fractal and Fractional, 2021 In this paper, electrochemical impedance responses of subdiffusive phase transition materials are calculated and analyzed for one-dimensional cell with reflecting and absorbing boundary conditions.
Pavel E. L’vov +3 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mathematics, 2023 Understanding the effect of vortexes on sound propagation is of great significance in the field of target detection and acoustic imaging. A prediction algorithm of the two-dimensional vortex scattering is realized based on a finite-difference frequency ...
Yongou Zhang +3 more
doaj +1 more source
Absorbing boundary conditions for electromagnetic wave propagation [PDF]
Mathematics of Computation, 1999 In this paper, the theoretical perfectly absorbing boundary condition on the boundary of a half–space domain is developed for the Maxwell system by considering the system as a whole instead of considering each component of the electromagnetic fields individually. This boundary condition allows any wave motion generated within the domain to pass through
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source