Results 71 to 80 of about 237,588 (284)
Donsker-Varadhan asymptotics for degenerate jump Markov processes [PDF]
We consider a class of continuous time Markov chains on a compact metric space that admit an invariant measure strictly positive on open sets together with absorbing states. We prove the joint large deviation principle for the empirical measure and flow.
Basile, Giada, Bertini, Lorenzo
core
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Site-bond representation and self-duality for totalistic probabilistic cellular automata
We study the one-dimensional two-state totalistic probabilistic cellular automata (TPCA) having an absorbing state with long-range interactions, which can be considered as a natural extension of the Domany-Kinzel model.
Atman A P F +10 more
core +1 more source
Evaluation of Potential Residual Silica as Antireflective Layer for Selective Solar Surface of Black Chromium [PDF]
Selective surfaces have the function of absorbing strongly the sunlight, while ideally losing little heat to the environment via convection and radiation.
Ithyara Dheylle Machado Medeiros +4 more
doaj +1 more source
Independent and monochromatic absorbent sets in infinite digraphs
AbstractLet D be a digraph, we say that it is an m-coloured digraph if the arcs of D are coloured with at most m-colours. An (u,v) arc is symmetrical if (v,u) is also an arc of D. A directed path (resp. directed cycle) is monochromatic if all of its arcs are coloured with the same colour, and it is quasi-monochromatic if at most one of its arcs is ...
Alejandro Contreras-Balbuena +2 more
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
We report the first experimental test of an analytic image reconstruction algorithm for optical tomography with large data sets. Using a continuous-wave optical tomography system with 10^8 source-detector pairs, we demonstrate the reconstruction of an ...
Colak +13 more
core +1 more source
We consider the Dirichlet problem for a class of degenerate nonlinear elliptic fourth-order equations with strengtheningly monotone principal parts, absorbing lower-order terms and L1-right-hand sides.
Francesco Nicolosi +1 more
doaj
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

