SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice
ABSTRACT Background Cachexia is a wasting syndrome associated with imbalanced energy metabolism and loss of adipose and muscle tissues and contributes to morbidity and mortality in ageing as well as in patients with severe chronic diseases, including cancer. At present, there are no treatments addressing cachexia that have reached validation to be used
Kang Xu +12 more
wiley +1 more source
The Gambian Bone and Muscle Ageing Study: Baseline Data from a Prospective Observational African Sub-Saharan Study [PDF]
The Gambian Bone and Muscle Ageing Study is a prospective observational study investigating bone and muscle ageing in men and women from a poor, subsistence farming community of The Gambia, West Africa.
Aboderin +36 more
core +2 more sources
NOVEL DIRECTION IN ADHERENCE ASSESSMENT — FOCUS ON THE GERIATRIC SYNDROMES
Aim. To investigate on the factors determining the adherence to optimal treatment in older age patients with chronic heart failure (CHF) in outpatient setting.Material and methods.
I. I. Chukaeva +3 more
doaj +1 more source
Weight/height2: Mathematical overview of the world's most widely used adiposity index
Summary A footnote in Adolphe Quetelet's classic 1835 Treatise on Man described his algebraic analysis of how body weight ( W) varies with height ( H) in adult males and females. Using data on 12 short and 12 tall subjects of each sex, Quetelet established the rule that W is approximately proportional ( ∝) to H2 in adults; that is, W∝H2 when W≈αH2 for ...
Steven B. Heymsfield +7 more
wiley +1 more source
Reduced sleep duration affects body composition, dietary intake and quality of life in obese subjects. [PDF]
Purpose Sleep duration has emerged as a crucial factor affecting body weight and feeding behaviour. The aim of our study was to explore the relationship among sleep duration, body composition, dietary intake, and quality of life (QoL) in obese ...
DI LAZZARO, Luca +11 more
core +1 more source
The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring
Osteoporosis is a common metabolic bone disease that seriously affects the quality of life and health of patients. Traditional diagnostic methods, such as dual energy X-ray absorptiometry (DXA), have limitations in early detection and dynamic monitoring,
Jie Fu, Chi Zhang, Chi Zhang
doaj +1 more source
Teriparatide is a bone-forming therapy for osteoporosis that increases bone quantity and texture, with uncertain action on bone geometry. No data are available regarding its influence on bone strain.
Carmelo Messina +9 more
doaj +1 more source
Abstract Chronological age has been the standard for quantifying the aging process. While it is simple to quantify it cannot fully discern the biological variability of aging between individuals. The growing body of interest in this variability of human aging has led to the introduction of new biomarkers to operationalize biological age.
Radin Alikhani +3 more
wiley +1 more source
Publications of the space physiology and countermeasures program, Musculoskeletal Discipline: 1980-1990 [PDF]
A 10-year cumulative bibliography of publications resulting from research supported by the musculoskeletal discipline of the space physiology and countermeasures program of NASA's Life Sciences Division is provided.
Dickson, Katherine J. +3 more
core +1 more source
Body segment parameters of Paralympic athletes from dual-energy X-ray absorptiometry [PDF]
The final publication is available at Springer via http://dx.doi.org/10.1007/s12283-016-0200-3This research represents the first documented investigation into the body segment parameters of Paralympic athletes (e.g., individuals with spinal cord injuries
AS Goktepe +20 more
core +1 more source

